中西医结合治疗120例新生儿黄疸疗效分析.docVIP

中西医结合治疗120例新生儿黄疸的疗效分析 　　摘要：目的探讨中西医结合治疗新生儿黄疸临床疗效。方法选取我院收治的120例新生儿黄疸患儿，采取数字表法随机分为观察组和对照组各60例，对照组患儿采用蓝光辅助苯巴比妥钠治疗，观察组患儿采用蓝光辅助茵栀黄颗粒联合苯巴比妥钠治疗。结果观察组患儿黄疸退尽时间(5.67±2.54)d明显短于对照组；胆红素日平均下降值(48.78±24.54)μmol/L、治疗总有效率（98.33%）明显高于对照组(P＜0.05)。结论中西医结合治疗可迅速降低血清胆红素，减少黄疸的发生率，提高小儿生活质量。 　　关键词：新生儿；黄疸；蓝光；苯巴比妥钠；茵栀黄 　　Clinical Analysis of 120 Cases of Neonatal Jaundice Treated with Combination of Chinese Traditional and Western Medicine 　　DING Ze-qing 　　(Zhoukou City Chuanhui District Hospital of Traditional Chinese Medicine,Zhoukou 466000,Henan,China) 　　Abstract：ObjectiveTo explore the clinical curative effect of combination of traditional Chinese and Western medicine treatment of neonatal jaundice. MethodsA total of 120 cases of neonatal jaundice in our hospital were adopted, and randomly divided into observation group and control group with 60 cases in each group, control group were treated by blue light assisted phenobarbital treatment, observation group were treated by blue light assisted Yinzhihuang Granules Combined with phenobarbital treatment. ResultsThe observation group with jaundice as time (5.67 ± 2.54) d was significantly shorter than the control group; the average daily value of bilirubin decreased (48.78 ± 24.54) μ mol/L, the total effective rate (98.33%) was significantly higher than the control group (P 0.05). ConclusionTreatment can rapidly reduce serum bilirubin with combination of TCM and Western medicine, reduce the incidence of jaundice, improve the quality of life in children. 　　Key words：Neonate; jaundice;Blue; Phenobarbital; Yin Zhi Huang 　　新生儿黄疸是指出生28d内新生儿，因胆红素代谢异常，导致血中胆红素水平升高，临床表现为皮肤、黏膜、巩膜黄疸，是新生儿常见症状。未结合胆红素会产生潜在神经毒性，严重的甚至导致胆红素脑病，具有较高病死率，且后遗症较多。因此，临床加强对新生儿黄疸的治疗至关重要。我院采用蓝光辅助茵栀黄颗粒联合苯巴比妥钠的中西医结合的方式，对新生儿黄疸进行防治，取得的满意疗效。现报告如下。 　　1资料与方法 　　1.1一般资料选取我院2010年1月～2014年2月收治的120例新生儿病理性黄疸患儿，其中男68例，女52例；胎龄(37.2±3.07)w；日龄2～28d；出生体质量(3197±137)g。所有患儿均符合第7版《儿科学》[1]新生儿病理性黄疸诊断标准：①黄疸出现于生后24h内；②足月儿血清胆红素＞221μmol/L，早产儿血清胆红素＞257μmol/L，或每日血清胆红素上升＞85μmol/L；③足月儿黄疸持续时间＞2w，早产儿持续时间＞4w；④