中西医结合治疗小儿原发性肾病综合征临床观察.docVIP

中西医结合治疗小儿原发性肾病综合征的临床观察 　　[摘要] 目的 探讨中西医结合治疗原发性小儿肾病综合征(PNS)的有效方法。方法 原发性肾病综合征患儿80例按照治疗方法不同分为:中西医结合组(A组)40例,西医治疗组(B组)40例,测定治疗前后PNS患儿的血清脂质水平血清胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平变化,比较两组疗效及不良反应。结果 A组总有效率95.0%,明显高于B组82.5%(χ2=4.24,P0.05);A组治疗后TC、TG、HDL-C、LDL-C含量均高于B组(t=2.220,t=2.307,t=2.344,t=2.319,P0.05);A组不良反应发生率6例(7.5%)低于B组9例(11.2%)(χ2=3.89,P0.05)。结论 中西医结合治疗原发性小儿肾病综合征明显优于单纯西药治疗。 　　[关键词] 原发性肾病综合征;小儿;中西医结合 　　[中图分类号] R272[文献标识码] A [文章编号] 1673-9701(2010)04-66-02 　　 　　Clinical Observation of Chinese and Western Medicine Combination for Primary Nephrotic Syndrome in Children 　　LIFuyuan 　　Department of Traditional Chinese Medicine,Huizhou Central Hospital,Huizhou 516001,China 　　 　　[Abstract] Objective To explore an effective way to the treatment of primary nephrotic syndrome (PNS) by combining Chinese and Western medicine. Methods We divided 80 cases of PNS in children according to different treatment ways into: Chinese and Western medicine combination group(Group A, 40 cases) and Western medicine group(Group B, 40 cases). The serum levels of cholesterol(TC),triglycerides (TG),high-density lipoprotein cholesterol(HDL-C) and low-density lipoprotein cholesterol(LDL-C) were measured before and after treatment. The curative efficacy and adverse reactions were compared between the two groups. Results The total effective rate of Group A was 95.0%, significantly higher than that(82.5%) of Group B(χ2=4.24, P0.05). The serum levels of TC, TG, HDL-C and LDL-C in Group A after treatment were higher than those of Group B(t=2.220,t=2.307,t=2.344,t=2.319,P0.05). The adverse reactions of Group A(6 cases,7.5%) were significantly lower than those of Group B(11.2%)(χ2=3.89,P0.05). Conclusion The curative effect of Chinese and Western medicine combination in the treatment of children with PNS is superior to that of Western medicine alone. 　　[Key words] Primary nephrotic syndrome;Children;Combination of Chinese and Western medicine 　　肾病综合征(PNS)是一组由多种原因引起的肾小球基膜通透性增加,导致血浆