依达拉奉联合氯吡格雷治疗急性脑梗死临床研究.docVIP

依达拉奉联合氯吡格雷治疗急性脑梗死的临床研究 　　[摘要]目的 探讨急性脑梗死患者采用依达拉奉联合氯吡格雷治疗的效果。方法 选取2015年6月～2017年6月我院收治的120例急性脑梗死患者作为研究对象，按照随机数字表法将患者分为两组，每组60例。对照组患者采用氯吡格雷进行治疗，实验组患者采用依达拉奉联合氯吡格雷进行治疗。比较两组患者的临床效果以及日常生活能力量表（ADL）评分和神经功能（NIHSS）评分。结果 实验组患者的治疗总有效率（90.00%）高于对照组（66.67%），差异有统计学意义（P0.05）。治疗后，两组患者的ADL和NIHSS评分均低于本组治疗前，实验组患者的ADL和NIHSS评分低于对照组，差异均有统计学意义（P0.05）。结论 在急性脑梗死患者的治疗中应用依达拉奉联合氯吡格雷可以改善患者的症状，对神经功能和生活质量的改善和转变有着重大的作用，值得临床治疗中推广应用。 　　[关键词]依达拉奉；氯吡格雷；急性脑梗死；临床效果 　　[中图分类号] R000 [文献标识码] A [文章编号] 1674-4721（2018）1（c）-0105-03 　　Clinical study of Edaravone combined with Clopidogrel in the treatment of acute cerebral infarction 　　LI Tian-bao YAN Xin-zheng WANG Hai-yan 　　Department of Neurology，the Ninth People′s Hospital of Nanhai District in Foshan City，Guangdong Province，Foshan 528203，China 　　[Abstract]Objective To investigate the efficacy of Edaravone combined with Clopidogrel in the treatment of acute cerebral infarction.Methods 120 patients with acute cerebral infarction treated in our hospital from June 2015 to June 2017 were selected as subjects.All patients were randomly divided into two groups according to the random number table method，60 cases in each group.The control group was treated with Clopidogrel，and the experimental group was treated with Edaravone combined with Clopidogrel.The clinical efficacy，the activity of daily living scale （ADL） score and neurological function （NIHSS） score of the two groups were compared.Results The total effective treatment rate in the experimental group （90.00%） was higher than that in the control group （66.67%），and the difference was statistically significant （P0.05）.After treatment，both ADL and NIHSS scores in two groups were lower than those before treatment，and the scores of ADL and NIHSS in the experimental group were lower than those in the control group，and the differences were statistically significant （P0.05）.Conclusion The application of Clopidogrel combined with Edaravone in treatment of acute cerebral infarction patients can improve the patient′