光动力联合甘草锌治疗寻常型痤疮疗效观察.docVIP

光动力联合甘草锌治疗寻常型痤疮疗效观察 　　doi：10.3969/j.issn.1007-614x.2014.18.47 　　摘要目的：观察光动力联合甘草锌治疗寻常型痤疮的临床疗效。方法：将符合纳入标准的60例寻常型痤疮患者随机分为两组。其中治疗组32例予光动力联合甘草锌治疗，对照组28例仅予光动力治疗，治疗时间4周。观察患者治疗前后的皮损变化，治疗结束后随访2个月评估复发情况。结果：治疗组有效率96.87%，对照组89.29%，差异有统计学意义（P0.05）。治疗组复发率明显低于对照组，差异有统计学意义（P0.05）。结论：光动力联合甘草锌治疗寻常型痤疮疗效好，复发率低，值得临床推广使用。 　　关键词寻常型痤疮光动力甘草锌 　　Curative effect observation of photodynamic therapy combined with licorzinc in the treatment of acne vulgaris 　　Xu Lihong，Zhong Ping，Chai Bao 　　The People’s Hospital of Nanshan District，Shenzhen City，Guangdong 518052 　　AbstractObjective：To observe the clinical effect of photodynamic therapy combined with licorzinc in the treatment of acne vulgaris.Methods：60 cases with acne vulgaris were included in the standard.They were randomly divided into two groups.32 cases of the treatment group were treated with photodynamic therapy combined with licorzinc.28 cases of the control group were only treated with photodynamic therapy.The treatment time was 4 weeks.The skin changes before and after treatment were observed. Follow-up 2 months after the end of treatment，the recurrence was evaluated.Results：The effective rate of the treatment group was 96.87%.The effective rate of the control group was 89.29%.There was significant differences （P0.05）.The relapse rate of the treatment group was significantly lower than that of the control group.There was also significant difference （P0.05）.Conclusion： The photodynamic therapy combined with licorzinc has a good curative effect and low relapse rate.It is worthy of promoting in clinical. 　　Key wordsAcne vulgaris；Photodynamic；Licorzinc 　　痤疮是皮肤科常见病，好发于青少年，是毛囊皮脂腺的慢性炎症，可表现为粉刺、丘疹、结节、囊肿及瘢痕等皮损，而且容易复发，往往给患者带来较重的精神负担。本研究于2013年1月-10月应用光动力联合甘草锌颗粒治疗寻常型痤疮，观察其临床疗效，现报告如下。 　　资料与方法 　　2013年1月-10月收治寻常型痤疮患者60例，按随机数字分为治疗组32例和对照组28例。 　　诊断标准：多在青春期起病，女性发病年龄较早。损害主要发生在面部，尤其是前额、颏部和双颊部，其次是胸部、肩部及背部。初起为粉刺，表现为圆锥形丘疹，有白头粉刺与黑头粉刺两种。白头粉刺为皮色丘疹，黑头粉刺表面呈黑色。粉刺可发展为炎性丘疹，一般为米粒至绿豆大小，如炎症继续发展，中心可有脓头，成为脓丘疹或脓疱，严重时形成结节及囊肿等。皮损逐渐融合，以囊肿为主，触之柔软有波动感，破溃后成为窦道或瘘管，在皮肤上