原发性高血压患者静息心率与代谢综合征关系及临床意义.docVIP

原发性高血压患者静息心率与代谢综合征关系及临床意义 　　[摘要] 目的 分析原?l性高血压患者静息心率增高与代谢综合征的关系。方法 方便选择2015年4月―2017年5月该院收治的原发性高血压患者320例作为研究对象，根据RHR水平分为3组，RHR 1组（RHR85次/min）110例，测量3组患者腰围、血压、FBG、糖负荷后2 h血糖、TC、TG、LDLC、HDLC、FINS、IR等指标。结果 与RHR1组和RHR2组相比，RHR3组的HDL最低[（0.74±0.45）mmol/L]，TC、TG、LDL、FINS、IR等指标[（5.92±0.73）mmol/L、（3.54±0.86）mmol/L、（4.01±0.68）mmol/L、（42.3±10.5）μU/mL、（12.7±1.76）]显著高于其他两组（P0.05）。3组合并1种代谢异常比率（35.5%）与合并2种代谢异常比率（42.7%）高于其他两组（P0.05）。RHR与腰围、FBG、糖负荷后2 h血糖、TC、TG、LDLC、FINS、IR呈正相关（r=0.36、0.61、0.45、0.28、0.45、0.41、0.36、0.54，P0.05），与HDLC呈负相关（r=-0.41，P0.05）。结论 RHR可能与原发性高血压患者代谢紊乱有关，在降压的同时应重视改善伴随的多种代谢紊乱及控制心率。 　　[关键词] 原发性高血压；静息心率；代谢综合征 　　[中图分类号] R544 [文献标识码] A [文章编号] 1674-0742（2017）08（c）-0009-03 　　Correlation and Clinical Significance of Resting Heart Rate and Metabolic Syndrome of Patients with Primary Hypertension 　　ZHANG Yan-xia， CHEN Gui-ling 　　Department of Cardiology， Anyang Third People’s Hospital， Anyang， Henan Province， 455000 China 　　[Abstract] Objective To analyze the correlation between the resting heart rate and metabolic syndrome of patients with primary hypertension. Methods 320 cases of patients with primary hypertension admitted and treated in our hospital from April 2015 to May 2017 were selected as the research objects and divided into three groups according to the RHR level， including RHR 1 group （RHP 85 times/min） with 110 cases， and the waistline， blood pressure， FBG， 2 h blood glucose after the glucose load， TC，TG，LDLC，HDLC，FINS，IR of the three groups were measures. Results The HDL in the RHR3 group was the lowest compared with that in the RHR 1 group and RHR 2 group， which was（0.74±0.45）mmol/L， and the TC，TG，LDL，FINS，IR were obviously higher than those in the other two groups， which were respectively[（5.92±0.73）mmol/L，（3.54±0.86）mmol/L，（4.01±0.68）mmol/L，（42.3±10.5）μU/mL，（12.7±1.76）]in the RHR 3 group（P 　　[Key words] Primary hypertension； Resting heart rate； Metabolic syndrome 　　静息心率（Resting heart rate，RHR）指人体在清醒、安静状态时心脏每分钟搏动次数，反映交感神经活性、自主神经平衡及机体代谢率水平[1]。研究表明[2]，静息