妊娠期糖尿病孕妇巨大儿血脂及血糖水平变化研究.docVIP

妊娠期糖尿病孕妇巨大儿血脂及血糖水平变化研究 　　[摘要]目的 探讨妊娠期糖尿病孕妇巨大儿的血脂及血糖水平变化。方法 选取2013年9月～2014年9月在本院确诊为妊娠期糖尿病孕妇分娩的42例巨大儿作为观察组，选取同期健康孕妇分娩的40例巨大儿作为对照组，选取健康孕妇分娩的40例健康足月体重正常（2.5～4.0 kg）新生儿作为健康组，测定孕妇及新生儿的空腹血糖、三酰甘油（TG）、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）及载脂蛋白A（ApoA）、载脂蛋白B（ApoB）水平，统计观察组和对照组孕妇的孕前BMI值和孕期增重程度并进行统计学分析。结果 观察组与健康组孕妇的LDL、HDL水平比较，差异无统计学意义（P0.05）。观察组孕妇的空腹血糖及TG水平显著高于健康组，差异有统计学意义（P0.05）。观察组孕妇的孕前BMI及孕期增重显著高于对照组，差异有统计学意义（P0.05）。观察组新生儿的TG水平高于对照组，ApoA、ApoB及血糖水平低于对照组，差异有统计学意义（P0.05）。观察组新生儿的TG水平高于健康组，ApoA、ApoB、血糖水平低于健康组，差异有统计学意义（P0.05）。结论 妊娠期糖尿病孕妇巨大儿的血脂、血糖水平较高，提高了新生儿低血糖等并发症的发生概率。 　　[关键词]妊娠期糖尿病；巨大儿；血脂与血糖 　　[中图分类号] R714.256 [文献标识码] A [文章编号] 1674-4721（2016）06（b）-0053-04 　　Study on the change of blood lipid and blood glucose level in macrosomia born by women with gestational diabetes 　　ZHANG Li-hong 　　Department of Obstetrics and Gynecology，the First People′s Hospital of Luoyang City，Luoyang 471002，China 　　[Abstract]Objective To explore the change of blood lipid and blood glucose level in macrosomia born by women with gestational diabetes.Methods 42 cases of macrosomia born by women diagnosed with gestational diabetes in our hospital from September 2013 to September 2014 were selected as the observation group.At the same time，another 40 cases of macrosomia born by healthy women were selected as the control group.40 full-term newborns who had normal weight （2.5-4.0 kg） and were born by healthy pregnant women were selected as the health group.The level of fasting blood glucose，triglyceride （TG），low density lipoprotein （LDL），high density lipoprotein （HDL），apolipoprotein A （ApoA） and apolipoprotein B （ApoB） in pregnant women and newborns were determined.The BMI before pregnancy and degree of weight gain during pregnancy of pregnant women in the observation group and the control group were statistically analyzed.Results There was no statistical difference in the level of LDL and HDL between pregnant women in the observation group and the healthy group （P0.05）.The level of fasting blood glucose and TG of pr