宁夏回汉族老年人血脂水平与载脂蛋白A1相关性研究.docVIP

宁夏回汉族老年人血脂水平与载脂蛋白A1相关性研究 　　【摘要】目的 研究宁夏回汉族老年人血脂水平的差异以及血脂与载脂蛋白A1的相关性。方法 以随机抽样的方法选取宁夏地区回汉族老年人885例，测其血脂及载脂蛋白A1水平，从而探讨载脂蛋白A1与血脂代谢的相关性。结果 ①汉族老年人总胆固醇水平和载脂蛋白A1水平均高于回族老年人（P0.05）；②载脂蛋白A1与总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇水平均呈正相关（P0.05），与甘油三脂水平呈负相关（P0.05）。结论 宁夏老年人血脂水平和载脂蛋白A1具有相关性，汉族老年人总胆固醇和载脂蛋白A1水平高于回族老年人。 　　【关键词】老年人；载脂蛋白A1；血脂代谢 　　【中图分类号】R589 【文献标识码】B 【文章编号】ISSN.2095-6681.2018.8..02 　　Correlation of ApoA1 with blood lipid level among Hui and Han elderly people in NingXia 　　YU Jingjing， MA Rong， HUANG Qi， JING Ming 　　（Ningxia Medical University General Hospital and biochip Beijing National Engineering Research Center Ningxia sub center， Ningxia Yinchuan 750004，China） 　　【Abstract】Objective To study the difference of blood lipid level between Hui and Han elderly people and the correlation of Apo A1 with blood lipid level.Methods Using random sampling method to recruit 885 subjects in Ningxia Hui Autonomous Region，Apo A1 levels and blood lipids levels were measured among subjects， and then study the correlation between Apo A1 levels and blood lipid metabolism among elderly people.Results ①The level of total cholesterol and apolipoprotein A1 （P0.05） of Han elderly people were higher than that of Hui elderly people.②Apolipoprotein A1 was positively correlated with total cholesterol， high-density lipoprotein cholesterol and low density lipoprotein cholesterol （P0.05） and was negatively correlated with triglyceride levels （P0.05） among elderly people.Conclusion There was a correlation between serum lipid level and apolipoprotein A1 among the elderly in Ningxia Hui Autonomous Region and the level of total cholesterol and apolipoprotein A1 of Han elderly people were higher than that of Hui elderly people. 　　【Key words】Elderly people；Apolipoprotein A1；lipid metabolism 　　血脂代?x异常是老年人的常见疾病，与心脑血管疾病、高血压、代谢综合征等疾病密切相关，严重的心脑血管疾病又是老年人致死、致残最严重的疾病之一，给老年人的家庭及社会带来了沉重的负担。随着我国经济的增长、生活水平的提高，血脂代谢异常的患病率逐年攀升[1]，血脂代谢与环境和遗传因素有关，已有大量研究表明血脂水平与载脂蛋白A1具有相关性[2-3]，本研究的的目是探讨宁夏回族自治区老年人血脂水平在不同民族间的分布差异，以及老年人血脂水平与载脂蛋白A1