TCT检查对宫颈病变173例诊断率临床分析-妇产科学专业论文.docxVIP

摘 摘 要 — — PAGE 1— TCT 检查对宫颈病变 173 例诊断率临床分析 研究生：伊丽达娜·米吉提 导师：马彩玲 教授 摘 要 目的：探讨我院 173 例可疑宫颈病变患者中液基薄层细胞学检测（TCT）在宫 颈病变诊断中的临床意义。方法：将新疆医科大学第一附属医院自 2008 年 6 月至 2009 年 9 月妇科门诊、住院部病房就诊行妇科检查疑似宫颈病变或体检常规行 TCT 检查结果提示异常的 173 例患者，对其年龄、民族、避孕方式、临床症状进行归纳、 分析研究的同时，行 TCT 检查，并与我院行阴道镜下宫颈可疑组织活检或对级别较 高者行宫颈锥切术，以阴道镜下病理学检查及宫颈锥切后病理结果做为金标准，分 析评价这 173 例患者中 TCT 检查的敏感度、特异度及假阴性率、假阳性率，并对不 同病理学级别宫颈病变所对应的 TCT 结果做一临床分析。结果：TCT 检测的敏感 度为 60%，特异度为 71.4%，假阴性率为 40%，假阳性率为 28.6%。随着宫颈组织 病理学级别的升高，TCT 的阳性率及敏感度分别为 48.7%、52.2%、62.1%和 89.5%， 呈上升趋势。结论：本研究中，随着宫颈组织病理学级别的升高，TCT 的敏感度随 之升高。TCT 与病理诊断有较高的符合率，可作为宫颈病变的一筛查指标，但它仍 存在一定的假阴性、假阳性率，不能以此作为判断宫颈病变的依据。 关键词：宫颈病变；宫颈癌；宫颈 CIN；TCT 新疆医科大 新疆医科大学医学硕士学位论文 Clinical Aspect of TCT in the diagnosis of Cervical lesions of 173 Cases Postguaduate：yilidana mijit Supervisor：Ma Cailing Professor Abstract Objective：To study the clinical value of thin-prep-liquid-based cytology tes（t TCT） in the diagnosis of our hospital’s 173 cases of cervical lesions.Methods：173 cases of patients from Junly 2008 to September 2009 in the first Subsidiary of Xin Jiang Medical University were screened by TCT，based on the pathology result as a golden standard，to aspect the sensitivity，specificity and fake negative rate of the TCT Test. Results：The postitive result cases of TCT were 84，the positive result cases of pathlology were 110. The sensitivity of TCT were 60%，the specificity were 71.4%，the fake negative rates were40%，the fake positive rates were 28.6%.In pace with the raise of pathological scalar ，the positive result rate of TCT were 48.7% ，52.2% ，62.1% and 89.5%. Conclusions：In this research，in pace with the raise of pathological scalar，the positive result rate of TCT were become higher and higher，and TCT can be one of cervical lesion screening technology，but it still has the fake negative rates and fake positive rats，it can not be used as a diagnosis foundation of cervical lesion. Key words: Cervical lesions；Cervical cancer；Cervical CIN； Thin-Liquid-based cytology test 论文独创性说明 本人申明所呈交的学位论文是在我个人在导师的指导下