小剂量多巴胺联合西地兰治疗小儿肺炎合并心力衰竭临床研究.docVIP

小剂量多巴胺联合西地兰治疗小儿肺炎合并心力衰竭临床研究 　　【摘要】 目的：探讨小剂量多巴胺联合西地兰在小儿肺炎合并心力衰竭治疗中的应用及其效果。方法：选择60例肺炎合并心力衰竭患儿，随机分为治疗组及对照组，每组各30例患儿，所有患儿均给予吸氧、平喘、抗感染等基础治疗，对照组患儿给予西地兰治疗，治疗组患儿给予小剂量多巴胺联合西地兰治疗，治疗3 d后评价两组患儿心功能参数及治疗效果。结果：治疗前两组患儿左心室射血分数（LVEF）、左心室射血前期（LPEP）、左心室射血期（LVET），二尖瓣E峰峰值血流速度/A峰峰值血流速度（E/A）、右心室射血前期（RPEP）、右心室射血期（RVET）比较差异均无统计学意义（P0.05）。治疗后治疗组患儿EF、LVET、RVET、E/A及总有效率均高于对照组，LPEP、RPEP均低于对照组，两组比较差异均有统计学意义（P0.05）。结论：小剂量多巴胺联合能够改善小儿肺炎合并心力衰竭患者心功能，提高临床效果，具有较好疗效。 　　【关键词】 多巴胺； 西地兰； 小儿； 肺炎； 心力衰竭 　　【Abstract】 Objective：To investigate the clinical application and effect of low dose dopamine combined cedilanid in children pulmonitis complicating congestive heart failure.Method：60 cases children with pulmonitis complicating congestive heart failure were selected，and randomly divided into control group and therapy group，30 cases in each group，all children were taken foundational treatment with inhaling oxygen， preventing asthma and anti-infection.Children in control group were taken cedilanid，and children in therapy group were taken low dose dopamine combined cedilanid，then parameter of heart function and curative effect were contrasted between two groups.Result：Before treatment，two groups of left ventricular ejection fraction（LVEF），left pre-ejection period（LPEP），left ventricular ejection time（LVET），and E/A， right pre-ejection period（RPEP）， right ventricular ejection time （RVET） had no statistically significant difference（P0.05）.After treatment， LVEF ， LVET， E/A， RVET and clinical effective in the therapy group were higher than the control group， LPEP， RPEP in the therapy group were lower than the control group， the differences were statistically significant（P0.05）.Conclusion：Low dose dopamine combined cedilanid can improve heart function in children pulmonitis complicating congestive heart failure， raise clinical effect and had satisfactory curative effect. 　　【Key words】 Dopamine； Cedilanid； Children； Pulmonitis； Congestive heart failure 　　First-author’s address：Longmen People’s Hospital of Guangdong