康莱特注射液配合化疗对晚期非小细胞肺癌治疗效果及免疫功能影响研究.docVIP

康莱特注射液配合化疗对晚期非小细胞肺癌治疗效果及免疫功能影响研究 　　[摘要]目的 探讨康莱特注射液配合化疗对晚期非小细胞肺癌患者治疗效果及免疫功能的影响。方法 选取2014年6月～2016年6月我院收治的64例晚期非小细胞肺癌患者作为研究对象，随机分为研究组和对照组，各32例。对照组采用化疗治疗，研究组在化疗的基础上联合康莱特注射液治疗。比较两组治疗前后的外周血T淋巴细胞亚群测定结果以及外周血免疫球蛋白测定结果。结果 研究组治疗后的CD3+、CD4+、CD8+水平高于对照组治疗后，差异有统计学意义（P0.05）。研究组治疗后的IgG水平为（9.71±0.35）mg/L，显著高于对照组治疗后的（8.19±0.30）mg/L，差异有统计学意义（P0.05）。结论 采用康莱特注射液配合化疗对晚期非小细胞肺癌患者进行治疗，能有效提高免疫功能，值得临床推广应用。 　　[关键词]康莱特注射液；化疗；晚期非小细胞肺癌；免疫功能 　　[中图分类号] R734.2 [文献标识码] A [文章编号] 1674-4721（2016）12（b）-0069-03 　　Influence study of therapeutic effect and immune function of Kanglaite Injection combined with chemotherapy on the advanced non-small cell lung cancer 　　ZHENG Wen HUANG Kai-rong RAO Min-chao 　　Department of Oncology，People′s Hospital of Shangrao City in Jiangxi Province，Shangrao 334000，China 　　[Abstract]Objective To explore the influence of therapeutic effect and immune function of Kanglaite Injection combined with chemotherapy on the advanced non-small cell lung cancer （NSCLC）.Methods 64 patients with advanced non-small cell lung cancer from June 2014 to June 2016 in our hospital were selected and randomly divided into the study group and the control group，32 cases in each group.The control group was treated with chemotherapy，and the study group was treated with Kanglaite Injection on the basis of the chemotherapy.The determination results of peripheral blood T lymphocyte subsets and peripheral blood immunoglobulin were compared between the two groups before and after treatment.Results The levels of CD3+，CD4+and CD8+ in the study group after treatment was higher than that in the control group after treatment，with significant difference （P0.05）.The level of IgG in the study group after treatment was （9.71±0.35）mg/L，which was higher than （8.19±0.30）mg/L in the control group after treatment，with significant difference （P0.05）.Conclusion Kanglaite Injection combined with chemotherapy in the treatment of advanced non-small cell lung cancer can effectively improve immune function，it is worthy