急性心肌梗死患者同型半胱氨酸超敏C反应蛋白检测临床意义.docVIP

急性心肌梗死患者同型半胱氨酸超敏C反应蛋白检测临床意义 　　[摘要]目的 探讨急性心肌梗死患者同型半胱氨酸、超敏C反应蛋白检测的临床意义。方法 收集2015年9月～2016年1月我院心内科确诊的急性心肌梗死患者94例作为探究组的研究对象，选择同期健康成年人94名作为对照组，探究组患者给予PCI治疗。采用酶联免疫吸附法和散射免疫比浊法检测研究对象的同型半胱氨酸、超敏C反应蛋白水平，比较探究组治疗前后同型半胱氨酸、超敏C反应蛋白的水平。结果 探究组患者的同型半胱氨酸、超敏C反应蛋白水平分别为（53.86±10.60）μmol/L、（47.52±27.38）ng/ml，高于对照组的（8.53±4.75）μmol/L与（2.41±1.93）ng/ml，差异有统计学意义（P0.05）。治疗后，探究组患者同型半胱氨酸水平与超敏C反应蛋白水平分别为（10.38±5.45）μmol/L、（7.15±3.14）ng/ml，均低于治疗前，差异有统计学意义（P0.05）。结论 急性心肌梗死患者体内的同型半胱氨酸与超敏C反应蛋白均出现不同程度的上升，临床上可通过检测以上两种物质的含量间接提示患者是否出现心肌梗死。 　　[关键词]急性心肌梗死；同型半胱氨酸；超敏C反应蛋白；PCI 　　[中图分类号] R542.2+2 [文献标识码] A [文章编号] 1674-4721（2016）07（a）-0044-03 　　[Abstract]Objective To explore the clinical significance of homocysteine and high sensitive C reactive protein in patients with acute myocardial infarction.Methods 94 patients with acute myocardial infarction that diagnosed in our internal medicine-cardiovascular department from September 2015 to January 2016 of were collected as study object（research group）.94 healthy adults at the same time were selected as control group.Patients in the research group were given PCI treatment.The levels of homocysteine and high sensitive C reactive protein were detected by enzyme linked immunosorbent assay and scatter immunoassay.The levels of homocysteine and high sensitive C reactive protein were compared before and after treatment in the research group.Results The level of homocysteine and C reactive protein in research group was respectively（53.86±10.60）μmol/L and （47.52±27.38）ng/ml，higher than （8.53±4.75）μmol/L and （2.41±1.93）ng/ml in control group respectively，with statistical difference（P0.05）.After treatment，the level of homocysteine and high sensitive C reactive protein in the research group were （10.38+5.45） mol/L，（7.15+3.14） ng/ml，lower than that of before treatment，the difference was statistically significant（P0.05）.Conclusion In patients with acute myocardial infarction，the same type of homocysteine and high sensitive C reactive protein in different degrees of rise，clinic