拉贝洛尔联合硫酸镁在妊娠期高血压治疗中临床价值分析.docVIP

拉贝洛尔联合硫酸镁在妊娠期高血压治疗中临床价值分析 　　【摘 要】目的：研究并分析拉贝洛尔联合硫酸镁对妊娠期高血压的临床治疗效果。方法：我院2009年12月-2013年12月期间共收治妊娠期高血压患者120例，随机分组，对照组的60例患者运用硫酸镁进行治疗，观察组的60例患者运用拉贝洛尔联合硫酸镁进行治疗，对比两组患者的治疗前后的血压改变情况、24小时尿蛋白变化情况以及产后并发症发生率。结果：与对照组患者相比，观察组患者的血压改善情况更为明显，差异具有显著性（P0.05）；观察组患者24小时尿蛋白水平低于对照组患者，差异具有显著性（P0.05）；观察组患者术后并发症发生率为10%，对照组患者术后并发症发生率为28.33%，差异具有显著性（P0.05）。结论：拉贝洛尔联合硫酸镁可有效改善妊娠期高血压患者的血压水平，且安全、有效，值得推广。 　　【关键词】拉贝洛尔；硫酸镁；妊娠期高血压；临床价值 　　【 abstract 】 objective：to study and analyze the labetalol in combination with magnesium sulfate the clinical therapeutic effect of gestational hypertension.Methods：our hospital during the period of December 2009 - December 2013 a total of 120 patients with gestational hypertension treated，randomized，control group of 60 patients were treated with magnesium sulfate，the observation group of 60 cases of patients using labetalol in combination with magnesium sulfate treatment，compared two groups of patients before and after treatment of blood pressure change situation，the 24 hours urinary protein and the changes of postpartum complications.Results：compared with control group patients，the observation group to improve the patients blood pressure is more apparent，with significant difference（P 0.05）；Observation group of patients with 24 hours urine protein levels in patients than controls，with significant difference（P 0.05）；Observation group of patients the incidence of postoperative complications was 10%，control group patients the incidence of postoperative complications was 28.33%，with significant difference（P 0.05）.Conclusion：labetalol in combination with magnesium sulfate can effectively improve blood pressure levels in patients with gestational hypertension，and safe，effective and worth popularization. 　　【 key words 】 labetalol magnesium sulfate gestational hypertension clinical value 　　妊娠期高血压是临床中常见于妊娠期女性患者的疾病之一，多发生于妊娠20周以后，患者的主要临床症状为血压升高、蛋白尿、水肿等。相关研究资料显示，将近10%的妊娠期女性均会出现不同程度的妊娠期高血压，若患者未得到及时治疗，极有可能出现抽搐、昏迷等，严重的将影响产妇与胎儿生命[1]。为了进一步分析拉贝洛尔联合硫酸镁治疗妊娠期高血压的临床疗效，我院开展本研究，并作出报告如