无痛内镜下注射止血联合大剂量埃索美拉唑治疗消化性溃疡出血临床研究.docVIP

无痛内镜下注射止血联合大剂量埃索美拉唑治疗消化性溃疡出血临床研究 　　[摘要]目的 探讨无痛内镜下注射止血联合大剂量埃索美拉唑治疗消化性溃疡出血的临床效果。方法 选取2015年3月～2017年2月我院收治的消化性溃疡出血患者90例，随机分为A组（大剂量埃索美拉唑治疗，30例）、B组（无痛内镜下注射止血联合常规剂量埃索美拉唑治疗，30例）、C组（无痛内镜下注射止血联合大剂量埃索美拉唑治疗，30例），比较三组患者止血时间、住院时间、住院费用及再次出血和手术发生率。结果 A组患者止血时间、住院时间、住院费用高于B、C两组，B组止血时间、住院时间、住院费用高于C组（P0.01）。A组患者再次出血发生率高于C组，手术率高于B、C两组（P0.05）。结论 无痛内镜下注射止血联合大剂量埃索美拉唑在消化性溃疡出血患者的治疗中可提高止血效果，降低再次出血发生率。 　　[关键词]消化性溃疡；出血；无痛内镜；埃索美拉唑 　　[中图分类号] R573.1 [文献标识码] A [文章编号] 1674-4721（2017）09（a）-0020-03 　　Clinical study of painless endoscopic injection of hemostasis combined with high dose Esomeprazole in the treatment of peptic ulcer bleeding 　　ZHOU Lei1 SU Chu-xia1 LI Chun-nan1 DING Zi-le2 　　1.Department of Gastroenterology，the People′s Hospital of Chao an District in Chaozhou City，Guangdong Province，Chaozhou 515638，China；2.Department of Anesthesiology，the People′s Hospital of Chao an District in Chaozhou City，Guangdong Province，Chaozhou 515638，China 　　[Abstract]Objective To investigate the clinical efficacy of painless endoscopic injection of hemostasis combined with high-dose Esomeprazole in the treatment of peptic ulcer bleeding.Methods 90 case of peptic ulcer bleeding patients in our hospital from March 2015 to February 2017 were selected and randomly divided into group A（30 patients with high-dose Esomeprazole），group B（painless endoscopic injection of hemostatic combined with conventional doses of Esomeprazole，30 patients），group C（painless endoscopic injection of hemostasis combined with high-dose Esomeprazole treatment，30 cases），The three groups of stop bleeding time，length of stay，hospital costs and re-bleeding and surgery were compared.Results The time of stop bleeding，hospitalization and hospital costs were higher in group A than those in group B and group C.The time of stop bleeding，hospitalization and hospital costs in group B were higher than those in group C（P0.01）.The rate of rebleeding was higher in group A than that in group C，and the rate of operation was higher than that of grou