无症状与症状性粥样硬化性大脑中动脉狭窄预后和影响因素探析.docVIP

无症状与症状性粥样硬化性大脑中动脉狭窄预后和影响因素探析 　　【摘要】 目的：探讨无症状和症状性粥样硬化性大脑中动脉狭窄的预后情况以及影响因素。方法：选择2010年1月-2012年1月笔者所在医院收治的急性脑卒中患者100例（症状性MCA狭窄组），另选取笔者所在医院同一时间收治的TCD筛查有MCA狭窄患者100例（无症状性MCA狭窄组），对所有患者给予2～4年的随访，比较两组脑卒中发生率以及相关高危因素。结果：无症状性MCA狭窄组中4例（4%）患者发生缺血性脑卒中，且糖尿病与出现脑卒中事件具有明显相关性（P0.05）；症状性MCA狭窄组24例（24.0%）患者复发脑卒中，且分析发现是否规律服用抗血小板药物与复发有相关性（P0.05）。结论：无症状MCIA狭窄患者预后相对良性，而糖尿病是导致其发生脑卒中的危险因素；症状性MCA狭窄患者脑卒中复发率高，且与是否规律服用抗血小板药物相关。 　　【关键词】 无症状； 症状性； 粥样硬化性； 动脉狭窄 　　中图分类号 R743.1 文献标识码 B 文章编号 1674-6805（2014）15-0126-02 　　The Prognosis and Factor Analysis of Asymptomatic and Symptomatic Atherosclerotic Middle Cerebral Artery Stenosis/ZENG Jing，LIU Xing-chen，WANG Feng，et al.//Chinese and Foreign Medical Research，2014，12（15）：126-127 　　【Abstract】 Objective：To study the prognosis and factor analysis of asymptomatic and symptomatic atherosclerotic MCA stenosis.Method：100 cases with acute stroke（symptomatic MCA stenosis group） were selected in our hospital from January 2010 to January 2012，100 cases of asymptomatic MCA stenosis（asymptomatic MCA stenosis group） which were admitted in the hospital by TCD screening at the same time were selected，all patients were followed-up 2 to 4 years，compared two groups of stroke incidence and related risk factors were compared.Result：4 cases（4%） in asymptomatic MCA stenosis group had stroke，the diabetes and stroke events occurring had significant correlation（P0.05），24 cases（24.0%） in symptomatic MCA stenosis group had recurrent stroke，regular antiplatelet drugs lead to relapse，there were significant differences（P0.05）.Conclusion：The prognosis of patients with asymptomatic MCIA narrow is relatively benign，and diabetes is affect the occurrence of the risk factors of stroke.Symptomatic MCA stenosis in patients with stroke recurrence rate is high，and it is associated with whether law antiplatelet medications. 　　【Key words】 Asymptomatic； Symptomatic； Atherosclerosis； Artery stenosis 　　First-author’s address：Zhongshan Hospital of TCM，Zhongshan 528400，China 　　脑动脉硬化是全身动脉硬化的一部分，且是