氯诺昔康对前交叉韧带重建术后镇痛安全性分析.docVIP

氯诺昔康对前交叉韧带重建术后镇痛安全性分析 　　[摘要]目的 探讨氯诺昔康对前交叉韧带重建术后镇痛的临床疗效与安全性，为临床提供更多的参考价值。方法 回顾性分析2013年9月～2015年9月我院收治的28例前交叉韧带重建术后疼痛患者，将其分为两组，对照组给予地佐辛，观察组予以氯诺昔康治疗，比较两组患者的VAS评分、镇痛满意度及不良反应发生情况。结果 与治疗前相比，两组治疗后6、12、18、24 h的VAS评分显著降低，差异有统计学意义（P0.05）；观察组不良反应发生率（7.14%）明显低于对照组（42.86%），差异有统计学意义（P0.05）；观察组患者优良满意度（85.71%）显著高于对照组（42.86%），差异有统计学意义（P0.05）。结论 氯诺昔康治疗前交叉韧带重建术后疼痛的临床效果较好，可有效降低不良反应发生率，具有较高的安全性，值得临床推广应用。 　　[关键词]氯诺昔康；前交叉韧带重建；术后镇痛；安全性 　　[中图分类号] R971+.1 [文献标识码] A [文章编号] 1674-4721（2016）10（c）-0112-03 　　[Abstract] Objective To investigate the clinical efficacy and safety of analgesia using Lornoxicam after anterior cruciate ligament reconstruction to provide more reference value for clinic.Methods 28 cases with anterior cruciate ligament reconstruction and postoperative pain treated by our hospital from September 2013 to September 2015 was retrospectively analyzed.They were divided into two groups，and control group was given Dezocine while observation group was given Lornoxicam.VAS score，analgesia satisfaction and incidence of adverse reaction in patients between two group was compared respectively.Results Compared with before treatment，VAS score after 6 h，12 h，18 h and 24 h was significantly lowered and the difference was statistically significant （P0.05）.Incidence rate of adverse reaction of observation group （7.14%） was significantly lower than that of control group （42.86%），and the difference was statistically significant （P0.05）. Good and excellent satisfaction in patients of observation group （85.71%） was significantly higher than that of control group （42.86%），and the difference was statistically significant （P0.05）.Conclusion The clinical efficacy of Lornoxicam treating postoperative pain after anterior cruciate ligament reconstruction is better，and it effectively reduce the incidence rate of adverse reaction with higher safety，it is worth to be popularized and applied in clinic. 　　[Key words]Lornoxicam；Anterior cruciate ligament reconstruction；Postoperative analgesia；Security