欣母沛联合卡孕栓预防巨大儿产妇剖宫产术产后出血临床分析.docVIP

欣母沛联合卡孕栓预防巨大儿产妇剖宫产术产后出血临床分析 　　[摘要] 目的 分析卡前列素氨丁三醇（欣母沛）?合卡前列甲酯栓（卡孕栓）防治巨大儿产妇剖宫产术中及术后出血的效果及安全性。方法 方便选取2015 年2月―2016 年8 月呼和浩特市第一医院40例巨大儿产妇剖宫产术胎儿，娩出后按使用宫缩剂不同分为两组，对照组和试验组，各20例，两组均宫体注射缩宫素20 IU，对照组同时宫体注射欣母沛250 μg；试验组同时宫体注射欣母沛250 μg+舌下含服卡孕栓1 mg 。观察两组术中、术后2 h的出血量及总出血量并定量，并观察不良反应。结果 两组手术时间差异无统计学意义（P0.05），两组术中出血量、术后2 h出血量及总出血量均有显著性差异（P0.05），试验组术中、术后2 h、总出血量分别为（286.5±67.3）mL，（87.6±32.7）mL，（374.0±97.5）mL，而对照组分别为（347.8±99.6）mL，（115.4±48.1）mL，（463.2±119.3）mL。不良反应对照组6例，试验组5例，主要为恶心、呕吐，腹泻，血压轻度升高，短时间内消失。结论 在常规使用缩宫素基础上，剖宫产术中联合使用欣母沛和卡孕栓，术中、术后出血量减少，不良反应少。 　　[关键词] 卡前列素氨丁三醇；卡前列甲酯；巨大儿；产后出血 　　[中图分类号] R71 [文献标识码] A [文章编号] 1674-0742（2017）09（b）-0113-03 　　[Abstract] Objective This paper tries to observe the effect and safety of hemabate combined with carboprost in the treatment of cesarean section and postoperative bleeding of macrosomia. Methods 40 cases of maternal cesarean section from February 2015 to August 2016 in Hohhot First Hospital were convenient selected and randomly divided into two groups， the control group and the experimental group， with 20 cases in each group， the control group was given the uterus injection of oxytocin 20 IU combined with hemabate 250 μg； the experimental group was treated with hemabate of 250 μg and the sublingual carprost of 1 mg. The blood loss and total blood loss during and two hours after the cesarean section were calculated and the adverse reactions were observed. Results There was no significant difference in the operation time between the two groups （P0.05）. The blood loss during and two hours after operation and the total blood loss was significantly different between the two groups（P0.05）. The total blood loss during and two hours after the cesarean section and the total blood loss of the experimental group were（286.5±67.3）、（87.6±32.7）、（374±97.5）mL， while the control group were （347.8±99.6）mL，（115.4±48.1）mL， （463.2±119.3）mL. As for the adverse， 6 cases in the control group， and 5 cases in the experimental group， mainly accompanied with nausea， vom