瑞舒伐他汀钙片治疗原发性高血压疗效观察.docVIP

瑞舒伐他汀钙片治疗原发性高血压疗效观察 　　【摘要】目的 观察瑞舒伐他汀片治疗原发性高血压的疗效。方法 选取我院收治的原发性高血压患者120例，随机分为治疗组和对照组，各60例。对照组给予常规低脂、低盐饮食，口服左旋氨氯地平片5 mg/d 　　治疗，治疗组在对照组的基础上，加服瑞舒伐他汀片，10 mg/d。观察并比较两组患者治疗前后血压和血脂的变化。结果 治疗前两组患者的血压和血脂水平比较差异均无统计学意义（P0.05），治疗后两组患者的收缩压、舒张压均明显降低（P0.05），差异均有统计学意义（P0.05）。结论 瑞舒伐他汀具有明显降低血脂和血压的作用，治疗原发性高血压疗效确切，安全可靠。 　　【关键词】瑞舒伐他汀；原发性高血压；高脂血症；疗效 　　【中图分类号】R544.1 【文献标识码】A 【文章编号】ISSN.2095-6681.2015.16.00.03 　　Rui shu laval statin calcium treatment curative effect observation of primary hypertension 　　WANG Dong-wei，LIU Yu-qing，ZHANG Juan，ZHANG Yan-xia，MAI Yu-lan，QIN Xiang-hao 　　（Zhengzhou Central Hospital Affiliated to Zhengzhou University，Henan Zhengzhou 450007，China） 　　【Abstract】Objective To observe the curative effect of the treatment of essential hypertension with the treatment of the patients with essential hypertension.Methods 120 patients with essential hypertension were randomly divided into treatment group and control group，60 cases in each group，the control group received conventional low fat，low salt diet，5 mg/d treatment，the treatment group on the basis of the control group，plus 10 mg/d.Blood pressure and blood lipid were observed and compared before and after treatment in the two groups.Results There was no significant difference in blood pressure and blood lipid levels between the two groups before treatment（P0.05）.The systolic blood pressure and diastolic blood pressure of the two groups were significantly decreased（P0.05），the difference was statistically significant（P0.05）.Conclusion The effect of the treatment of essential hypertension and the effect of the treatment of essential hypertension is effective，safe and reliable. 　　【Key words】The essential hypertension；Essential hypertension；Hyperlipidemia；Curative effect 　　随着我国人民物质生活水平的不断提高，原发性高血压的患病率也随之逐年升高，高血压是心、脑血管疾病的重要危险因素。近年来许多临床研究证明，他汀类药物除了具有较强的降脂作用外，还具有一定的降压作用，本文旨在进一步探讨瑞舒伐他汀片对原发性高血压的治疗作用。 　　1 资料与方法 　　1.1 一般资料 　　选择2010年11月～2012年10月我院收治的原发性高血压患者120例作为研究对象。所有患者均符合2005年《中国高血压防治指南（修订版）》中的诊断标准[1]。排除标准：继发性高血压、急性心肌