瑞芬太尼和舒芬太尼在合并心血管疾病患者普外科手术麻醉中应用效果分析.docVIP

瑞芬太尼和舒芬太尼在合并心血管疾病患者普外科手术麻醉中应用效果分析 　　 　　[摘要] 目的 探讨瑞芬太尼和舒芬太尼在合并心血管疾病患者普外科手术麻醉中的应用效果。 方法 选取本院2012年1月～2014年1月收治的60例合并心血管疾病的患者，将其随机分为对照组和观察组，分别采用瑞芬太尼和舒芬太尼进行手术麻醉，观察两组患者的手术相关指标，总结两种手术麻醉方法的临床效果。 结果 两组麻醉效果差异无统计学意义（P0.05）。观察组术后清醒时间长于对照组，气管拔管时间短于对照组，差异有统计学意义（P0.05）。 结论 瑞芬太尼和舒芬太尼用于合并心血管疾病患者的手术麻醉均安全有效，但舒芬太尼的镇痛持续时间更长，镇痛强度更大，临床应用效果更好。 　　[关键词] 心血管疾病；瑞芬太尼；舒芬太尼 　　[中图分类号] R971+.2[文献标识码] A[文章编号] 1674-4721（2014）04（c）-0077-03 　　 　　Efficacy analysis of remifentanil and sufentanil on general surgical anesthesia in patients with cardiovascular disease 　　LIU Hua 　　Department of Anesthesiology,the Third People′s Hospital of Nanhai Distirct,Foshan City in Guangdong Province,Foshan 528244,China 　　[Abstract] Objective To explore the efficacy of remifentanil and sufentanil on general surgical anesthesia in patients with cardiovascular disease.Methods 60 cases of patients with cardiovascular disease in our hospital from January 2012 to January 2014 were accepted,and were divided into control group and observation group.The control group were given with remifentanil while the observation group were received sufentanil.The surgery-related indicators were observed and the clinical result was summarized.Results The total anesthetic effective rate of two groups had no significant difference (P0.05).Postoperative recovery time in observation group was longer than that of the control group,the extubation time was shorter than that of the control group,the difference was significant (P0.05).Conclusion Remifentanil and sufentanil anesthesia for cardiovascular patients is safe and effective,but sufentanil has longer duration of analgesia,greater analgesic potency and better clinical application. 　　[Key words] Cardiovascular disease;Remifentanil;Sufentanil 　　目前，心血管疾病患者逐年增多，大部分患者在进行手术治疗时常会出现心脏不良事件及围术期并发症，很容易出现心律失常、急性心肌梗死、充血性心力衰竭等[1-2]。合理地选择麻醉手术对于降低心血管患者非心脏手术心脏不良事件的发生具有重要意义。瑞芬太尼和舒芬太尼都是临床上常用的麻醉性镇痛药，两者都是新型阿片受体激动剂，瑞芬太尼作用时间短，对血流动力学通常影响较小，舒芬太尼常用于长时间大手术麻醉[3]。本研究探讨采用瑞芬太尼和舒芬太尼进行手术麻醉的临床效果。 　　1 资料与方法 　　1.1