生大黄对内镜下逆行胰胆管造影术后胰腺炎预防作用.docVIP

生大黄对内镜下逆行胰胆管造影术后胰腺炎预防作用 　　[摘要]目的 探讨内镜下逆行胰胆管造影术（ERCP）后应用生大黄对胰腺炎的预防作用。方法 选取2014年3月～2016年3月萍乡市人民医院收治的采用ERCP术治疗的胰腺炎高危患者164例为研究对象，按照入院顺序分成观察组与对照组，每组各82例。对照组手术前后均实施常规治疗，观察组在此基础上于术前1 d及术后3 h口服生大黄浸泡液进行通便。比较两组术后胰腺炎及高淀粉酶血症的发生情况，观察两组的通便时间及其他并发症发生情况。结果 观察组术后胰腺炎发生率为2.44%，较对照组（7.32%）显著降低（P0.05）；观察组通便时间[（10.26±3.26）h]明显短于对照组[（19.54±4.69）h]（P0.01）；两组术后均无其他严重并发症发生。结论 生大黄可明显降低患者ERCP术后的胰腺炎的发生率，缩短通便时间，对于胰腺炎有明显预防作用，临床应用价值高。 　　[关键词]内镜下逆行胰胆管造影术；生大黄；胰腺炎；预防；通便时间 　　[中图分类号] R657.51 [文献标识码] A [文章编号] 1674-4721（2016）11（a）-0021-03 　　Clinical observation of the effect of Rhubarb on the prevention of pancreatitis after ERCP 　　XU Lin-fang1 LIAO Wen2 　　1.Department of Gastroenterology，Pingxiang People′s Hospital，Jiangxi Province，Pingxiang 337000，China；2.Department of Nephrology，Pingxiang People′s Hospital，Jiangxi Province，Pingxiang 337000，China 　　[Abstract]Objective To investigate the preventive effect of Rhubarb on acute pancreatitis after ERCP.Methods From March 2014 to March 2016，164 patients with high-risk factors of pancreatitis who were treated by ERCP in Pingxiang People′s Hospital were selected as the study objects，and they were divided into observation group and control group，with 82 cases in each groups.The control group was given the routine treatment before and after operation，the observation group was given Rhubarb Soak Laxative oral 1 d preoperative and 3 h postoperative on the basis of routine treatment. The occurrence of postoperative pancreatitis and hyperamylasemia was compared between two groups；the defecation time and occurrence of other complications were observed.Results The incidence rate of postoperative pancreatitis in the observation group was 2.44%，was lower than that of the control group （7.32%） （P0.05）；the hyperamylasemia of the observation group [（10.26±3.26）h] was significantly shorter than that of the control group [（19.54±4.69）h] （P0.01）；there was no other serious complications happened in two groups.Conclusion Rhubarb can significantly reduce the incidence of