甲亢患者治疗前后血清FT3FT4PTH水平变化及CT改变情况临床价值分析.docVIP

甲亢患者治疗前后血清FT3FT4PTH水平变化及CT改变情况临床价值分析 　　【摘要】 目的 分析甲状腺功能亢进症（甲亢）患者治疗前后血清游离三碘甲状腺原氨酸（FT3）、游离甲状腺素（FT4）、甲状旁腺激素（PTH）水平的变化以及CT的改变情况。方法 50例健康体检者作为对照组， 50例甲亢患者作为观察组。比较观察组患者治疗前后血清P3+、Ca2+、FT3、FT4、PTH检测水平变化， 及其与对照组的差异， 并观察观察组患者治疗前后CT改变情况。结果 观察组患者治疗前的PTH水平低于本组治疗后和对照组， FT4、FT3水平高于本组治疗后和对照组， 差异均具有统计学意义 （P0.05）。观察组患者治疗前的P3+ （2.85±1.38）pmol/L、Ca2+ （3.86±1.85）pmol/L水平高于本组治疗后[（1.33±0.21）、（2.03± 　　0.69）pmol/L]和对照组[（1.58±0.32）、（2.45±0.32）pmol/L]， 差异均具有统计学意义（P0.05）。观察组患者CT影像中， 治疗前主要表现为钙化、边界欠清晰、单发低密度结节， 治疗后主要表现为右叶前后最大直径为20.5 mm， 在横断面上可见马蹄形、蝶形。结论 甲亢患者经治疗后， 血清FT3、FT4和PTH水平均呈改善趋势， 且逐渐正常化。 　　【关键词】 甲状腺功能亢进症；血清游离三碘甲状腺原氨酸；血清游离甲状腺素；甲状旁腺激素；CT 　　DOI：10.14163/j.cnki.11-5547/r.2017.33.007 　　Clinical value analysis of changes of serum FT3， FT4， PTH levels and CT changes before and after treatment in patients with hyperthyroidism CHEN Dan-dan. Department of Radiology， Hubei Traditional Chinese Medicine Hospital， Wuhan 430074， China 　　【Abstract】 Objective To analyze the changes of serum free triiodothyronine （FT3）， free thyroxine （FT4）， parathyroid hormone （PTH） levels and CT changes before and after treatment in patients with hyperthyroidism. Methods There were 50 healthy examinees as the control group， and 50 patients with hyperthyroidism as observation group. Comparison were made on changes of serum P3+， Ca2+， FT3， FT4 and PTH level in the observation group before and after treatment， and its difference with the control group. The changes of CT before and after treatment in the observation group were observed. Results The observation group had lower PTH level before treatment than after treatment and the control group， and higher FT4， FT3， than after treatment and the control group. Their difference was statistically significant （P0.05）. The observation group had P3+ as （2.85±1.38） pmol/L， Ca2+ as （3.86±1.85）pmol/L before treatment， which were higher than after treatment [（1.33±0.21） and （2.03± 　　0.69） pmol/L] and the control group [（1.58±0.32） and （2.45±0.32） pmol/L]. Their difference was sta