纳美芬在急性一氧化碳中毒患者抢救中应用价值.docVIP

纳美芬在急性一氧化碳中毒患者抢救中应用价值 　　[摘要] 目的 分析纳美芬在急性一氧化碳中毒患者抢救中的应用价值。方法 在该院2013年2月―2017年2月实施治疗的急性一氧化碳中毒患者中随机选取54例，依照治疗方式分成两组，其中对照组和观察组，对照组患者实施基础治疗，观察组患者加上纳美芬治疗，对比两组患者临床效果。 结果 和对照组患者相比，观察组患者的临床治疗总有效率显著偏高，差异有统计学意义（P0.05），其中对照组和观察组患者的临床治疗总有效率分别为70.4%和92.6%；和对照组患者相比，观察组患者的昏迷时间、意识恢复时间、住院时间均显著偏短，差异有统计学意义（P0.05），其中对照组患者的昏迷时间、意识恢复时间、住院时间分别为（9.7±1.3）h、（12.2±2.3）h、（4.8±0.3）d，观察组患者则分别为（6.4±1.2）h、（8.9±1.0）h、（2.0±0.5）d；和对照组患者，观察组患者的HDS评分和APACHE评分具有显著优势，差异对比有统计学意义（P0.05），其中对照组患者的HDS评分和APACHE评分分别为（12.4±2.1）分、（22.2±3.5）分，观察组分别为（21.6±2.9）分、（13.5±2.8）分。 结论 纳美芬在急性一氧化碳中毒患者抢救中的应用，能够显著提高患者临床效果，值得推广。 　　[关键词] 纳美芬；急性一氧化碳中毒；抢救 　　[中图分类号] R595 [文献标识码] A [文章编号] 1674-0742（2017）08（c）-0145-03 　　Application Value of Nalmefene in the Rescue of Patients with Acute Carbon Monoxide Poisoning 　　GE Zhen-zhong 　　Department of Emergency， Wuxi People’s Hospital， Wuxi， Jiangsu Province， 214023 China 　　[Abstract] Objective To analyze the application value of nalmefene in the rescue of patients with acute carbon monoxide poisoning. Methods 54 cases of patients with acute carbon monoxide poisoning treated in our hospital from February 2013 to February 2017 were randomly selected and divided into two groups according to the treatment method， the control group adopted the basic treatment， while the observation group adopted the nalmefene treatment on the basis of the control group， and the clinical effect was compared between the two groups. Results The total clinical treatment effective rate in the observation group was obviously higher than that in the control group， and the difference was obvious was stctistically significant，（92.6% vs 70.4%）（P0.05）， and the coma time， awareness recovery time and length of stay in the observation group were obviously shorter than those in the control group， and the differences was stctistically significant（P0.05）， [（6.4±1.2）h，（8.9±1.0）h，（2.0±0.5）d vs （9.7±1.3）h，（12.2±2.3）h，（4.8±0.3）d]， and the HDS score and APACHE score in the observation group had an obvious advantage， and the di