脾氨肽治疗小儿反复呼吸道感染临床疗效观察.docVIP

脾氨肽治疗小儿反复呼吸道感染临床疗效观察 　　【摘要】 目的：分析探讨脾氨肽（复可托）治疗反复呼吸道感染的临床疗效。方法：选取本院近年来收治的60例反复呼吸道感染患者作为研究对象，按照数字抽签法将其随机分为研究组与对照组，每组30例，研究组在常规治疗的基础上行复可托治疗，对照组仅行常规治疗，比较两组治疗效果。结果：研究组治疗显效率为56.7%，总有效率为90.0%，对照组治疗显效率为23.3%，总有效率为50.0%，研究组患者治疗效果明显优于对照组（P0.05）。与治疗前相比，研究组患者治疗后CD8指标出现明显下降，CD3、CD4、CD4/CD8指标出现明显上升，治疗前后研究组患者T细胞亚群指标比较差异有统计学意义（P0.05）。结论：复可托治疗反复呼吸道感染可改善患者免疫失衡状态，具有显著的临床疗效。 　　【关键词】 脾氨肽； 小儿反复呼吸道感染； 免疫失衡 　　Clinical Observation Spleen Aminopeptidase （Stoeckel care） Treatment of Recurrent Respiratory Tract Infections/ZENG Sheng-rong， DING Shu-juan.//Medical Innovation of China，2014，11（28）：076-079 　　【Abstract】 Objective： To investigate the spleen ammonia peptide （complex） clinical curative effect for the treatment of recurrent respiratory tract infections. Method： To select 60 patients admitted in our hospital in recent years， patients with recurrent respiratory tract infections as the research object， according to the digital lottery method were randomly divided into research group and control group， 30 cases in each group， the team in uplink compound could be the basis of routine therapy treatment， the control group only routine treatment， compare therapeutic effect of the two groups. Result： Team treatment efficiency was 56.7%， total effective rate was 90.0%， the control group’s treatment efficiency was 23.3%， total effective rate was 50.0%， the team with the treatment effect was better than the control group （P0.05）. Compared with before treatment， the team CD8 index after treatment in patients with decreased obviously， CD3， CD4， CD4 / CD8 indicators appeared obvious rise， before and after treatment group patients with T cell subgroup index comparison difference was statistically significant （P0.05）. Conclusion： Compound can improve the patients immune treatment of recurrent respiratory tract infections is imbalance， has significant clinical effect. 　　【Key words】 Spleen aminopeptidase； Recurrent respiratory infections； Immune imbalance 　　First-author’s address： The First Peoples