腹腔镜手术与开腹手术对结肠癌患者胃肠功能和免疫功能影响.docVIP

腹腔镜手术与开腹手术对结肠癌患者胃肠功能和免疫功能影响 　　[摘要] 目的 探?腹腔镜手术与开腹手术对结肠癌患者胃肠功能和免疫功能的影响。 方法 选取本院2014年1月～2016年1月收治的100例结肠癌患者，根据临床术式不同将其分为观察组、对照组两组，每组各50例，对照组患者采用开腹手术，观察组患者采用腹腔镜手术。比较两组患者术后胃肠功能恢复情况，包括术后肠鸣音恢复时间、术后排气时间及两组患者手术前后各项免疫功能指标的变化情况。 结果 观察组患者术后肠鸣音恢复时间（37.8±9.1）min，术后排气时间（3.1±0.9）h，均显著短于对照组，差异有统计学意义（P0.05）。对照组患者术后第1天IgA、IgM、IgG均较术前第1天显著降低，差异有统计学意义（P0.05）。 结论 结肠癌患者行腹腔镜手术有利于促进患者术后肠功能恢复，对免疫功能影响小，与开腹手术相比具有显著优势，值得推广和应用。 　　[关键词] 结肠癌；腹腔镜；胃肠功能；免疫功能 　　[中图分类号] R735.3+5 [文献标识码] A [文章编号] 1673-9701（2016）35-0015-03 　　Effect of laparoscopic surgery and laparotomy on gastrointestinal function and immune function in the patients with colon cancer 　　CHENG Tao FAN Lihua TENG Xianglong GUO Jingquan ZOU Wujun 　　Department of Anorectal Surgery， Lishui People’s Hospital in Zhejiang Province，Lishui 323000，China 　　[Abstract] Objective To investigate the effects of laparoscopic surgery and laparotomy on gastrointestinal function and immune function in the patients with colon cancer. Methods A total of 100 patients with colorectal cancer who were admitted to our hospital from January 2014 to January 2016 were selected. They were divided into the observation group and the control group according to the different clinical procedures， with 50 cases in each group. The patients in the control group were treated with open surgery， and the patients in the observation group were treated with laparoscopic surgery. The recovery of gastrointestinal function was compared between the two groups of patients， including the recovery time of postoperative bowel sounds， postoperative time of passage of gas and the changes of immune function indices before and after the operation in the two groups were compared. Results The recovery time of postoperative bowel sound was（37.8±9.1） min and the time of postoperative passage of gas was（3.1±0.9） h in the observation group， which were significantly shorter than those in the control group， and the differences between two groups were statistically significant（P0.05）. IgA， IgM a