腹腔镜手术联合GnRH―a治疗子宫内膜异位症伴不孕患者疗效分析.docVIP

腹腔镜手术联合GnRH―a治疗子宫内膜异位症伴不孕患者疗效分析 　　【摘要】 目的：探讨子宫内膜异位症伴不孕患者采用腹腔镜手术联合GnRH-a治疗的临床疗效。方法：回顾性分析2012年12月-2016年12月本院收治的子宫内膜异位症伴不孕患者75例的临床资料，根据患者就诊号将其分为观察组（单号）38例和对照组（双号）37例。对照组患者采用腹腔镜手术治疗，观察组患者采用腹腔镜手术联合GnRH-a治疗。比较两组患者的治疗效果、妊娠率、复发率及不良反应发生情况。结果：观察组患者显效率、总有效率、妊娠率分别为52.63%、97.37%、34.21%，均高于对照组的29.73%、81.08%、13.51%，比较差异均有统计学意义（P0.05）。结论：腹腔镜手术联合GnRH-a治疗可有效提高子宫内膜异位症的临床效果及患者妊娠率。 　　【关键词】 腹腔镜； GnRH-a； 子宫内膜异位症伴不孕； 疗效 　　Efficacy of Laparoscopy Surgery Combined with GnRH-a in Treatment of Endometriosis with Infertility/LI Shi，JIN Sufang，MA Wenjun.//Medical Innovation of China，2018，15（07）：021-024 　　【Abstract】 Objective：To investigate the clinical effect of laparoscopy combined with GnRH-a in treatment of endometriosis with infertility.Method：The clinical data of 75 cases of endometriosis with infertility treated in our hospital from December 2012 to December 2016 were retrospectively analyzed.According to the number of patients，they were divided into 38 cases of observation group（single number） and 37 cases of control group（double number）.The control group was treated with laparoscopic surgery，and observation group was treated with laparoscopic surgery combined with GnRH-a.The treatment effect，pregnancy rate，recurrence rate and the occurrence of adverse reactions between two groups were compared.Result：The effective rate，total effective rate and pregnancy rate of observation group were 52.63%，97.37% and 34.21% respectively，which were higher than 29.73%，81.08%，13.51% in control group，the differences were statistically significant（P0.05）.Conclusion：Laparoscopic surgery combined with GnRH-a can effectively improve the clinical effect and pregnancy rate of patients with endometriosis. 　　【Key words】 Laparoscopy； GnRH-a； Endometriosis with infertility； Curative effect 　　First-author’s address：Shenzhen Hospital of Guangzhou University of Chinese Medicine，Shenzhen 518034，China 　　doi：10.3969/j.issn.1674-4985.2018.07.006 　　子宫内膜异位症是妇科临床常见疾病，可造成患者不孕或慢性盆腔疼痛，好发于育龄期女性，是女性生育年龄阶段常见疾病[1-2]，患病率10%～1