腹腔镜手术联合化疗治疗子宫内膜癌近远期效果分析.docVIP

腹腔镜手术联合化疗治疗子宫内膜癌近远期效果分析 　　[摘要] 目的 探讨腹腔镜手术联合化疗治疗子宫内膜癌的近远期效果，旨在为提高患者生活质量并延长生命提供理论依据。 方法 选择2012年10月～2013年10月在我院接受治疗的子宫内膜癌患者156例，随机将其分成研究组和对照组，每组各78例，对照组患者接受腹腔镜手术治疗，研究组患者给予腹腔镜联合化疗治疗，比较两组患者的治疗有效率、局部复发率、远处转移率以及3年生存率；对两组患者躯体功能、心理功能、社会功能、物质生活等方面评分；统计两组患者并发症率。 结果 研究组患者治疗有效率为87.18%，局部复发率为7.69%，远处转移率为6.41%，3年生存率为83.33%，均显著优于对照组（75.64%、16.67%、11.54%、66.67%），差异有统计学意义（P0.05）；研究组患者躯体功能评分为（81.05±3.16）分，心理功能评分为（83.59±4.03）分，社会功能评分为（86.42±4.68）分，物质生活评分为（80.11±2.71）分，均显著优于对照组[（76.64±2.05）、（70.94±3.11）、（72.58±2.51）、（71.39±2.17）分]，差异有统计学意义（P0.05）；研究组患者胃肠道反应、骨髓抑制、肾损伤、白细胞下降、血小板下降等并发症发生率显著高于对照组，差异有统计学意义（P0.05）。 结论 腹腔镜手术联合化疗治疗子宫内膜癌其近远期效果显著，但是化疗易引起不良反应，临床治疗应密切监测患者血细胞水平。 　　[关键词] 腹腔镜手术；化疗；子宫内膜癌；并发症 　　[中图分类号] R737.33 [文献标识码] A [文章编号] 1674-4721（2016）05（b）-0050-04 　　[Abstract] Objective To explore the long-dated curative effect of laparoscopic surgery combined with chemotherapy in treating endometrial cancer and to provide theoretical foundation for enhancing life quality and prolonging life of patients. Methods 156 endometrial cancer patients from October 2012 to October 2013 of our hospital were selected and were random average divided into study group and control group.Patients in control group were given laparoscopic surgery and patients in study group were given laparoscopic surgery combined with chemotherapy.The treatment effective rate，local recurrent rate，distant metastatic rate and three-year survival rate in two groups were compared.The physical function，psychological function，social function and material life in two groups were scored.The complications rate in two groups was counted. Results The effective rate，local recurrent rate，distant metastatic rate and three-year survival rate in study group were respectively 87.18%，7.69%，6.41% and 83.33%，which was better than that of control group （75.64%，16.67%，11.54%，66.67%），and the differences were statistically significant （P 　　[Key words] Laparoscopic surgery；Chemotherapy；Endometrial cancer；Complications 　　子宫内膜癌是女性生殖系统发病率较高的一种恶性肿瘤，发病