腹腔镜手术中使用米非司酮联合甲氨蝶呤对术后持续性异位妊娠发生影响.docVIP

腹腔镜手术中使用米非司酮联合甲氨蝶呤对术后持续性异位妊娠发生影响 　　【基金项目】南宁市卫生局科技计划项目。 　　【第一作者简介】宁旦（1979-），男，主治医师、硕士，主要从事产科临床诊治与研究工作 　　DOI:10.3969/j.issn.1672-1993.2014.07.009 　　【摘要】目的:探讨腹腔镜手术联合术中米非司酮联合甲氨碟呤预防输卵管妊娠后持续性异位妊娠临床疗效和安全性。方法:选择2012年11月至2013年8月之间在我院行腹腔镜进行输卵管妊娠手术的患者84名，按照随机数字表的将患者分为治疗组和对照组,两组患者均为42名。治疗组行腹腔镜手术，并在术中向腹腔及卵巢输注米非司酮联合甲氨碟呤；对照组患者仅给予腹腔镜手术。比较两组患者的手术时间、术后出血量、术后温度及住院时间和血hCG值。结果:两组患者经腹腔镜下手术后手术时间（min）及术后出血量（mL）比较具有差异性，P＜0??05；而两组患者在术后体温（℃）及住院天数以及血hCG比较没有差异，P＞0??05。结论:在临床中，腹腔镜手术联合术中米非司酮联合甲氨碟呤可以更好的控制输卵管妊娠后持续性异位的发生率，且安全性较好，值得在临床上重视。 　　【关键词】腹腔镜手术；米非司酮；甲氨蝶呤；输卵管妊娠；异位妊娠 　　The clinical curative effect and safety of mifepristone combined methotrexate during laparoscopic surgery for preventing persistent ectopic pregnancy after tubal pregnancy NING Dan, NING Feng. Department of Obstetrics, Nanning city maternal and child health care hospital ,Nanning 530011,China 　　【Abstract】Objectives: To investigate the clinical curative effect and safety of mifepristone combined methotrexate during laparoscopic surgery for preventing persistent ectopic pregnancy after tubal pregnancy. Methods:84 cases laparoscopic tubal pregnancy surgery patients treated from November 2012 to August 2013 in our hospital,they were divided the patients into two groups by random number table,they were the treatment group(cases=42) and the control group(cases=42),respectively, the treatment group were given mifepristone combined methotrexate during laparoscopic surgery,the control group patients were given the laparoscopic surgery,.the operation time,intraoperative blood loss,postoperative temperature and length of hospital stay and blood hCG level were compared. Results:There were statistical different in the operation time,intraoperative blood loss of two groups patients after laparoscopic surgery,P0.05. There were statistical different in the postoperative temperature and length of hospital stay and blood hCG level of two groups patients after laparoscopic surgery,P0.05. Conclusions:The clinical curative effect a