阿托伐他汀联合曲美他嗪治疗冠心病疗效观察.docVIP

阿托伐他汀联合曲美他嗪治疗冠心病疗效观察 　　[摘要] 目的 对阿伐他汀与曲美他嗪联合治疗冠心病的临床疗效进行分析。 方法 随机选取我院2013年1月～2015年1月共收治的66例冠心病患者，分为研究组和对照组。两组均给予阿伐他汀治疗，研究组加用曲美他嗪治疗，对比两组的治疗效果及安全性。 结果 研究组的总有效率显著高于对照组，不良反应发生率明显低于对照组；研究组的血脂水平改善情况、心血管事件及不良反应发生率等均显著优于对照组（P0.05）。 结论 阿伐他汀与曲美他嗪联合治疗冠心病能够有效改善患者症状及心功能，大大降低了心血管事件风险，且不良反应少，效果显著。 　　[关键词] 冠心病；阿伐他汀；曲美他嗪；不良反应 　　[中图分类号] R541.4 [文献标识码] B [文章编号] 1673-9701（2015）23-0092-03 　　The clinical efficacy of atorvastatin combined with trimetazidine in treatment of coronary heart disease 　　MA Huihui 　　Department of Internal Medicine， Binnan Hospital of Shengli Petroleum Administration Bureau in Shandong Province，Binzhou 256600， China 　　[Abstract] Objective To explore the clinical efficacy of atorvastatin combined with trimetazidine in treatment of coronary heart disease. Methods In our hospital from January 2013 to January 2015，66 patients with CAD were divided into study group and the control group. Both groups were given atorvastatin treatment， study group combined with the trimetazidine， therapeutic effects and safety were compared between two groups. Results The total effective rate of study group was significantly higher than the control group， incidence of adverse events was significantly lower than the control group； Lipid level of improving the situation， cardiovascular events and adverse reaction rates etc in study group was significantly better than the control group， with statistically significant difference （P0.05）. Conclusion Atorvastatin and trimetazidine combination in treatment of coronary heart disease can improve symptoms and heart function，reduce the risk of cardiovascular events， and fewer adverse reactions， the effect is significant. 　　[Key words] Coronary artery disease； Atorvastatin； Trimetazidine； Adverse reactions 　　冠心病是内科的常见病、多发病，也可称为缺血性心肌病，主要是冠状动脉狭窄及心肌供血不足而造成心肌功能障碍或心肌坏死所致[1]。超过90%的冠心病是由冠状动脉粥样硬化引起，致死率、致残率较高。冠心病的治疗多以最大程度地保护心功能为治疗原则[2]。2013年1月～2015年1月，我院采用阿托伐他汀与曲美他嗪联合治疗33例冠心病患者，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　选取2013年1月～2015年1月在我院进行治疗的66例冠心病患者作为本次研