黛力新对原发性失眠患者睡眠脑电图影响分析.docVIP

黛力新对原发性失眠患者睡眠脑电图影响分析 　　摘要：目的 分析黛力新对原发性失眠患者睡眠脑电图的影响。方法 选取2015年2月～2016年11月我院收治的原发性失眠患者114例，随机分为观察组与对照组，对照组患者给予艾司唑仑治疗，剂量为2 mg/d，观察组患者给予黛力新治疗，剂量为2片/d，对比两组患者睡眠脑电图所显示的睡眠结构、睡眠率及睡眠质量评分（PSQI）。结果 观察组患者治疗后S1、S2及REM均显著低于对照组（P0.05），S3、S4与对照组相比明显较高且差异有统计学意义（P0.05）；观察组患者睡眠率与对照组相比较高（P0.05），PSQI评分与对照组相比显著较低（P0.05）。结论 黛力新（氟哌噻吨美利曲辛片）对原发性失眠患者可促进睡眠结构改善，延长入睡时间，提高睡眠质量。 　　关键词：氟哌噻吨美利曲辛片；原发性失眠；睡眠脑电图 　　中图分类号：R256.23 文献标识码：A 文章编号：1006-1959（2017）21-0075-02 　　Analysis on Effect of Deanxit in Patients with Primary Insomnia Sleep EEG 　　ZHANG Bin-bin 　　（Department of Neurology，Dongli Hospital，Tianjin 300300，China） 　　Abstract：Objective To analyze the effect of Deanxit in the treatment of primary insomnia patients sleep EEG.Methods From February 2015 to November 2016 in our hospital 114 cases of primary insomnia patients，randomly divided into observation group and control group，the control group were treated with estazolam treatment，a dose of 2 mg of/d，patients in the observation group were given Deanxit treatment dose for the 2/d，the sleep structure were compared between two groups of sleep EEG shows，rate and quality of sleep score（PSQI）.Results The patients in the observation group after treatment of S1，S2 and REM were significantly lower than the control group（P0.05），S3，S4 compared with the control group was significantly higher and the difference was statistically significant（P0.05）；The sleep rate of the observation group was significantly higher than that of the control group （P 0.05），and the PSQI score was significantly lower than that of the control group（P0.05）.Conclusion Deanxit（Flupentixol and Melitracen Tablets）in patients with primary insomnia can promote sleep，improve the structure，prolong the sleep time，improve the quality of sleep. 　　Key words：Flupentixol and melitracen tablets；Primary insomnia；Sleep EEG 　　原?l性失眠主要表现为入睡困难、睡眠深度较浅、频度过短、睡眠质量差等症状，是临床常见疾病，多由忧虑、抑郁、恐惧等情绪导致，也可因压力过大引发，多发于青年或中年群体，并呈逐年上升趋势[1]。艾司唑仑是临床常用的抗原发性失眠药物，但治疗效果不理想。黛力新又称为氟哌噻吨美利曲辛片，为特异性神经阻滞剂，可有效调节中枢神经功能，主要用于改善中度心理疾患