CTA成像质量和造影剂注射速率相关性分析.docVIP

CTA成像质量和造影剂注射速率相关性分析 　　[摘要] 目的 讨论64层螺旋CT冠状动脉血管成像质量与造影剂注射速率间关系。 方法 整群选取该院2014年6月―2015年4月进行冠脉血管造影的患者90例，随机分3组，每组30例，分别以4、5、6 mL/s速率进行造影剂注射，同时进行64层螺旋CT扫描。延迟时间使用团注实验进行测定。结果 心脏血管、升主动脉及降主动脉对比，差异有统计学意义（P0.01）。心脏血管对比衰减与体重指数及体重间存在明显关联，差异有统计学意义（r=-0.603，0.742，P=0.024）；5 mL/s组图像质量明显优于其它两组，差异有统计学意义（P0.01）。 结论 在进行心脏CT血管造影（CTA）时，其它条件相同时，造影剂注射速率为5 mL/s所得图像质量最优，临床可以此为参考进行造影剂注射。 　　[关键词] 64层螺旋CT；CTA；造影剂；冠状动脉 　　[中图分类号] R [文献标识码] A [文章编号] 1674-0742（2015）11（b）-0181-02 　　[Abstract] Objective To discuss the relationship between quality of 64-slice spiral CT coronary artery angiography and injection speed of contrast media. Methods 90 patients who underwent coronary artery angiography in our hospital from June 2014 and April 2015 were randomly divided into three groups with 30 in each one. Patients in the three groups received contrast agent injection at speed of 4ml/s， 5ml/s， 6ml/s respectively together with 64-slice spiral CT scanning. Delay time was measured using test-bolus examination. Attenuation value of ascending aorta and descending aorta was measured in the left coronary artery crosssectional region of interest， and ardiovascular attenuation value was determined using multiplannar reconstruction on orthogonal section image which located 1cm away form the outlet. Results Statistically significant difference can be found in heart and blood vessels， ascending aorta， and descending aorta between the three groups，（P0.01）. Ardiovascular attenuation value was closely related with body mass index and body mass （r=-0.603， 0.742， P=0.024）. The image quality of patients who received contrast agent injection at speed of 5ml/s was better than those who received contrast agent injection at speed of 4ml/s and 6ml/s， and the difference between them was statistically significant，（P0.01）. Conclusion Patients who receives contrast agent injection at speed of 5ml/s for CTA can attain a best image quality when contrast agent concentration， scan condition and other factors was unchanged. This may