肺癌辨证分型和病理标本色象相关性研究.docVIP

肺癌辨证分型和病理标本色象相关性研究 　　摘要：目的验证并探讨“有诸内必形诸外”的理论。方法将126例肺癌术前的病人根据临床常见证候分为肺脾气虚证、肺阴虚证、气滞血瘀证、痰热阻肺证、气阴两虚证，对肺癌手术切除后的肿瘤组织的颜色进行判读后分类，并收集术后病理报告结果，最后进行统计。结果肺癌中医辨证分型与手术切除后肿瘤组织颜色、病理分型具有相关性。结论126例病例中腺癌以肺脾气虚证、气滞血瘀证为主，鳞癌以肺阴虚证为主，肺癌患者中医证型与病理组织类型具有相关性。在126例病例中肺脾气虚、肺阴虚、气滞血瘀患者其肿瘤组织颜色分别以白色、赤色、青色为主，具有统计学意义。肺癌患者各肿瘤组织颜色之间无统计学意义。 　　关键词：肺癌；辨证分型；病理组织；组织病理学；颜色；有诸内必行诸外 　　中图分类号：R273文献标志码：A文章编号：1007-2349（2016）09-0027-05 　　【Abstract】Objective： To verify and investigate the theory of Outer Appearance from the Inside. Methods： 126 preoperative lung cancer patients were divided into lung-spleen Qi-deficiency， lung-Yin deficiency， Qi-stagnation and blood stasis， phlegm-heat and lung obstruction and Qi-yin deficiency according to common clinical syndromes. After surgical resection， their tumor tissue colors were interpreted and classified and their postoperative pathological report results were collected and conducted statistically. Results： TCM syndrome differentiation of lung cancer patients had correlation with tumor tissue color and pathological classification after the surgical resection. Conclusion： Among 126 cases， glandular cancer was mainly oriented to lung-spleen Qi-deficiency and Qi-stagnation and blood stasis， and squamous carcinoma mainly to lung-Yin deficiency. TCM syndrome differentiation of lung cancer patients had correlation with pathological tissue types. The lung cancer patients with lung-spleen Qi-deficiency， lung-Yin deficiency， Qi-stagnation and blood stasis syndromes mainly had white， red and blue-based tumor tissues， with statistical significance. There is no statistical significance between lung cancer tumor tissue colors of the patients. 　　【Key words】lung cancer， syndrome type， pathological tissue， histopathology， color， Outer Appearance from the Inside 　　肺癌是目前世界上最常见、致死率最高的恶性肿瘤之一。[1]肺癌患者发病前、发病后都或多或少有其相应症状，正所谓“有诸内必形诸外”。本文就肺癌辨证分型，与手术切除后标本的色、质进行的相关性研究，使“病”与“证”的关系更加明确，使“有诸内必形诸外”更加客观。 　　1资料与方法 　　11一般资料收集126例病例全部来自于2014年1月―2015年3月期在成都中医药大学附属医院（四川省中医院）胸外科及四川省肿瘤医院（四川省第二人民医院）胸外科住