不同输血的策略对严重创伤大量输血并发ARDS的影响.docVIP

不同输血的策略对严重创伤大量输血并发ARDS的影响 　　【摘要】 目的：探究不同输血策略对严重创伤大量输血并发急性呼吸窘迫综合征（ARDS）影响。方法：选择本院120例严重创伤大出血需进行大量输血的患者作为研究对象，按照随机数字表法将患者分为治疗组和对照组，每组60例。对照组采用传统输血策略，治疗组采用早期干预凝血策略，观察对比两组不同输血策略对严重创伤大量输血并发ARDS的影响。结果：治疗组的ARDS发生率和死亡率均明显低于对照组，差异均有统计学意义（P0.05）。治疗组的氧合指数、PaO2和PaCO2均明显优于对照组，差异均有统计学意义（P0.05）。治疗组红细胞输注量、血小板计数均明显少于对照组，差异均有统计学意义（P0.05）。治疗组输血费用和总费用均明显少于对照组，差异均有统计学意义（P0.05）。结论：早期干预凝血的输血方案可以改善患者的凝血功能障碍，降低ARDS发生率和死亡率，减少肺损伤，减轻经济负担。 　　【关键词】 输血策略； 严重创伤； ARDS 　　The Effect of Different Blood Transfusion Strategies on ARDS in Severe Trauma Patients with Massive Blood Transfusion/YANG Tian-xing，ZENG Ya-li，YE Bi-hua，et al.//Medical Innovation of China，2017，14（12）：040-043 　　【Abstract】 Objective：To investigate the effects of different transfusion strategies on ARDS in severe trauma patients with massive blood transfusion.Method：A total of 120 patients with severe traumatic hemorrhage in our hospital were selected，they were divided into the treatment group and the control group according to random number table method，60 cases in each group.The control group adopted the traditional blood transfusion strategy，the treatment group adopted the early intervention strategy.The effect of different blood transfusion strategies on ARDS in severe trauma were observed and compared.Result：The incidence of ARDS and mortality of the treatment group were significantly lower than those in control group，the differences were statistically significant（P0.05）.The oxygenation index，PaO2 and PaCO2 were significantly better than those in control group，the differences were statistically significant（P0.05）.The erythrocyte transfusion and platelet count were significantly less than those in control group，the differences were statistically significant（P0.05）.The blood transfusion cost and total cost were significantly less than those in control group，the differences were statistically significant（P0.05）.Conclusion：Early intervention of blood coagulation can improve the coagulation function of patients， reduce the incid