肠易激综合征与精神心理因素的关系-中西医结合临床专业论文.docxVIP

— —1— 摘 要 肠易激综合征与精神心理因素的关系 研究生：王 海 导师：姚 萍 副教授 摘 要 目的：本研究采用症状自评量表（SCL-90）对肠易激综合征（Irritable bowel syndrome ,IBS）患者及对照组进行评定，进一步探讨 IBS 发病与精神心理因素之间 的关系。方法：应用症状自评量表（SCL-90）对就诊于新疆医科大学第一附属医院 消化科并确诊为 IBS 的 30 例患者与 30 例健康对照组进行心理因素评分，IBS 患者诊 断标准符合罗马 III 标准，排除吸收不良综合征、血吸虫感染、胃肠道肿瘤、溃疡性 结肠炎、Crohn 病、肠道菌群失调、肝胆及内分泌疾病、无神经系统及精神疾病史、 无药物和酒精滥用。采用 SPSS17.0 软件进行 t 检验分析，以 P＜0.05 作显著性差异 的检验标准。结果：症状自评量表（SCL-90）的结果显示 IBS 患者躯体化、人际关 系、抑郁、焦虑等因子得分均高于对照组，提示 IBS 患者普遍存在抑郁、焦虑、躯 体化、人际关系敏感等异常心理，以焦虑和抑郁更为突出（P＜0.05）。躯体化、焦虑 的因子得分，IBS 女性患者高于男性患者，差异有统计学意义（P＜0.05）。结论：IBS 患者普遍存在着不同程度的心理异常，主要表现为抑郁、焦虑、躯体化等症状，IBS 女性患者在躯体化及焦虑等因子得分高于男性患者。因此，精神心理因素异常可能 在 IBS 发病机制中起一定的作用。 关键词：心理因素； 肠易激综合征； 抑郁； 焦虑； 胃肠 新疆医科大学医学硕士学位论文 The Relationship between Irritable bowel syndrome and psychological factor in the patients Postgraduate: Wang hai Supervisor: Vice Professor Yao ping ABSTRACT Objective:To discuss the relationship between Irritable bowel syndrome and psychological factor in the patients.To investigate with SCL-90 both IBS patients and control group. Methods: Use SCL-90 to assess 30 patients with IBS and 30 volunteers were involved in the study,who visit in Digestive Department in Xinjiang Medical University and diagnose as IBS.The patients case definitions adjust to ROME III,and exclude malabsorption syndrome,Infection Schistosoma,gastrointestinal tract tumor,Ulcerative colitis, Crohns disease, alteration of intestina flora,diseases of liver and gall,diseases of endocrine,no Nervous System and mental illness,no Drug/Alcohol Abuse.Use SPSS17.0 to T verify analysis.Results:There were abnormal scores on depression, anxiety, panic, compulsion idea, and hypersensitivity of people relation, depression and anxiety (P＜0.05) were obvions in IBS patients, show that IBS patients ubiquit abnormity psychology: depression, anxiety, panic, compulsion idea.The scores in somatization and anxiety, the female higher than male patients, the difference have a statistics significance. Conclusion: IBS patients have the abnormal psychologica