柴朴汤治疗191例慢性咳嗽临床的研究.docVIP

柴朴汤治疗191例慢性咳嗽临床的研究 　　摘要：目的 观察柴朴汤治疗慢性咳嗽的临床疗效。方法 纳入191例慢性咳嗽柴朴汤方证患者，开展多中心临床观察。给予柴朴汤颗粒剂，每日1剂，早晚分服，共服7～14剂。于治疗前及治疗1、2周填写中医证候积分量表，观察中医疗效和中医症状改善情况。结果 治疗1、2周的有效率分别为84.3%（161/191）、97.9%（187/191）。治疗2周的咳嗽消失率为67.01%（128/191）；除咽痒、咽中物堵外，单项症状有效率均90%，其中寒热往来、胸闷、呕恶、心烦、胁痛有效率位居前列，分别为98.8%、97.9%、97.9%、97.2%、96.6%。结论 柴朴汤对慢性咳嗽柴朴汤方证患者有良好治疗效果。 　　关键词：柴朴汤；慢性咳嗽；疗效 　　DOI：10.3969/j.issn.1005-5304.2017.04.008 　　中图分类号：R259.6 文献标识码：A 文章编号：1005-5304（2017）04-0029-03 　　Clinical Study on Treatment of 191 Patients with Chronic Cough by Chaipo Decoction ZHANG Li-shan1， ZHOU Shao-zhong1， ZHANG Shun-li2， TIAN Ai-ping3， CHEN Yi-chuan4， QIN Dong-feng5， WANG Yun-chuan6， GUO Wei1 （1. Dongzhimen Hospital， Beijing University of Chinese Medicine， Beijing 100700， China； 2. The Second Hospital Affiliated to Tianjin University of Chinese Medicine， Tianjin 300150， China； 3. Hebei Province Cangzhou Hospital of Integrated Traditional and Western Medicine， Cangzhou 130900， China； 4. Bijie Hospital of Chinese Medicine， Bijie 551700， China； 5. Liaocheng Hospital of Chinese Medicine， Liaocheng 252000， China； 6. Baoshan Hospital of Chinese Medicine， Baoshan 678000， China） 　　Abstract： Objective To study the efficacy of Chaipo Decoction on chronic cough. Methods Totally 191 patients with chronic cough treated with Chaipo Decoction syndrome were included to conduct multi-center clinical observation. The patients were given Chaipo Decoction Granules， 1 dose each day， morning and night， 7-14 doses in total. TCM syndrome integral scales were filled before treatment and 1 week and 2 weeks after treatment to observe TCM efficacy and TCM symptom improvement. Results After 1 and 2 week of treatment， the total effective rate was 84.3% （161/191）， 97.9% （187/191）， and disappearance rate of cough was 67.01% （128/191）. Except for pharyngeal itching and pharynx material block， the effective rate of single symptom 90%， among which the effective rates of cold and heat， chest tightness， vomitting， upset， and hypochondriac pain were in