二茂铁衍生物的电化学行为与抗氧化活性分析-有机化学专业论文.docxVIP

Abstract Since the last century, synthesis and properties of ferrocene derivatives has been investigated further. It promotes the research progress of the organic metallic compounds effectively. The development of organic electrochemical analysis is also promoted very well, which makes the organic electrochemical research enters a new phase. Meanwhile, the exploration on the ferrocene derivatives is changing gradually from theory to application in the field of organic catalysis, functional materials, molecule probe and so on. Now, research of these organic derivatives of electrochemical activity is limited, it is disadvantage of application of the ferrocene derivatives. So, it is necessary that to be discussed more on their electrochemical behaviors and relative biological activity, physiological function. Presently, the removed ability to DPPH · free-group is used commonly on their antioxidative capacities. However, they are tedious, long experimental cycle and more influence factors in this method steps. The electrochemical method will be assayed to be substitute for the general antioxidative ability measurement of chemical substance. In this article, the main contents are as follows: 1）The 1# - 4# samples are different from nitro substituents position on benzene rings in chalcone-ferrocene derivant. Influences of nitro-group on electrochemical reversible degree are measured by using CV and the removing efficiency of DPPH· free group. The changing tendency of anti-oxidative ability is in accordance with the angle differential values, which is between anodic and cathodic branch lines of the peak current density to the square of scan rate. Therefore, the descending order of chalcone-ferrocene derivant samples is 4# 3# 2# 1#, i.e., sample with para- meta- ortho- nitro without nitro in benzene ring. 2）6# - 8# samples, differently from single pentadienoic ring in ferrocene derivatives, are investigated by the above-mentioned methods. Thus, their antioxidant orde