胰岛素检测的方法及其临床的应用.docVIP

胰岛素检测的方法及其临床的应用 　　摘要： 目的：研究胰岛素的检测方法，分析对比研究结果意义，并探讨胰岛素检测的临床价值。方法：采用化学发光免疫分析法对294例2型糖尿病患者与同期健康者在空腹状态下进行胰岛素检测，其中217例2型糖尿病患者作为本次研究的实验组，另外77例同期健康者作为对照组。同时对其进行胰岛素检测结果分析，根据检测结果来探讨胰岛素在临床上的应用价值。结果：在217例2型糖尿病患者中，血液胰岛素的测定结果为（60.7±17.5）mU/L，77例同期健康者对照组中，血液胰岛素的测定结果为（16.2±8.9）mU/L，差异有统计学意义（P0.05）。 结论：化学发光免疫分析法可以有效的检测机体内血液胰岛素的浓度，胰岛素的检测在糖尿病及其临床疾病的深入探讨研究有重大意义，运用化学发光免疫分析法检测胰岛素有助于临床判断糖尿病病情，为临床诊断治疗提供指导依据。 　　关键词：胰岛素； 检测方法；化学发光免疫分析法；糖尿病 　　Abstract：Objective：Observe the effects of thalidomide treatment of elderly patients and relapsed multiple myeloma clinical efficacy and effectiveness and safety， and to explore the most effective mechanism for the treatment of senile relapsed multiple myeloma.Method：clinical observation on 13 cases of primary treatment and 12 patients above 60 years of age with recurrent elderly myeloma patients， were made of arsenic trioxide combined with thalidomide treatment， intravenous arsenic trioxide for 10mg/d which， at the same time， the continuous injection 28 days， oral low dose thalidomide 100 200mmg/d， according to the actual situation of patients may be appropriate to increase， the maximum the limit is 300mg/d， 28 days for a course of treatment， taking two courses of treatment， efficacy and side effects were observed during the evaluation of curative effect， in accordance with the standard EBM T effect， according to the NCI CTCAECTCAE （National Cancer Institute Common Terminology Criteria for Adverse Events， version 3） standard to evaluate the adverse reaction.Result：in the 13 patients newly diagnosed 5 cases of partial remission （38.46%）， 5 cases of progress （38.46%）， and 3 cases ineffective （23.08%）. In 12 cases of senile multiple myeloma patients， 4 cases of partial remission （33.3%）， 5 cases （41%） had improvement， 3 cases （25%） are invalid， the total effective rate was 74.3%. Observed that， in the treatment of common adverse reactions are nausea and fatigue， abdominal distension and constipation， skin rash， liver injury， neutropenia， but after trea