四肢躯干侵袭性纤维瘤13例临床剖析.docVIP

四肢躯干侵袭性纤维瘤13例临床剖析 　　[摘要] 目的 研究四肢关节侵袭性纤维瘤的诊断治疗方法。 方法 通过2010年1月～2014年12月我院收治13例四肢躯干侵袭性纤维瘤患者病例报道，总结该病治疗经验。 结果 中青年女性占全部患者比例53.84%，乳腺发病率23.07%，根据术后按照Enneking肿瘤分期，良性肿瘤10例，低度恶性3例；随访过程中，局部复发率为7.69%。 结论 四肢躯干部位侵袭性纤维瘤多发于乳腺及肌肉、肌腱丰富部位，青年女性好发，局部侵袭性生长，但不发生转移的肿瘤，临床诊断主要以病理形态学为依据，治疗方法主要以手术局部扩大切除为主，复发因素多于肿瘤体积、低度恶性程度及手术中是否做到切缘阴性有关，预后较好。 　　[关键词] 肿瘤；侵袭性纤维瘤；诊断；治疗 　　[中图分类号] R738.6 [文献标识码] B [文章编号] 1673-9701（2015）20-0047-04 　　Clinical analysis of 13 cases aggressive fibromatosis on limbs and trunk 　　JIA Yuqing1 GENG Chunyuan2 WEI Huiming1 TENG Yufei1 YAO Haiyu1 　　1.Department of Orthopaedic，the Fourth Hospital of Jilin university （FAW hospital），Jilin Province， Changchun 130000，China；2.Department of Joint and Sports Medicine，the Bethune First Hospital of Jilin University，Jilin Province， Changchun 130000，China 　　[Abstract] Objective To summarize the diagnosis and treatment of aggressive fibromatosis on limbs and trunk. Methods All 13 cases of aggressive fibromatosis were reported to summarize the experience of treatment during January 2010 to December 2014. Results The proportion of middle and young female was 53.84% in all cases. The incidence of breast was 23.07%. According to Enneking staging of tumor，10 cases were benign and 3 cases were low malignant potential. The recurrence rate was 7.69% during the follow-up. Conclusion The breast and the part which is plentiful of muscle and tendon in young-aged women are susceptible to the aggressive fibromatosis. Local invasive growth and no metastasis is the basic characteristic of the aggressive fibromatosis. Clinical diagnosis is mainly depended on pathological test. The extended resection is effective treatment.The recurrence rate is related to the volume of tumor，malignant potential and whether the margin of extended resection is clean.The prognosis is good. 　　[Key words] Tumor； Aggressive fibromatosis； Diagnosis； Treatment 　　侵袭性纤维瘤病又称硬纤维瘤或韧带样纤维瘤，是一种少见的软组织肿瘤疾病，由成纤维细胞异常增生所致，好发于年轻女性。现阶段学者多因为侵袭性纤维瘤不发生恶变及转移而认为该肿瘤属于良性病变，但其局部侵袭性生长，易复发，其病理形