糖尿病下肢血管病变彩色多普勒超声诊断剖析.docVIP

糖尿病下肢血管病变彩色多普勒超声诊断剖析 　　【摘要】 目的 评价彩色多普勒超声对糖尿病(DM)下肢血管病变(LEAD)的诊断应用价值。方法 DM患者106例与100例同期健康志愿者进行下肢血管彩色多普勒超声检查对照。结果 糖尿病组106例患者，发现100例下肢动脉有不同程度粥样硬化改变，检出率为94．3%。糖尿病组的血管内径较对照组明显减低；血流量亦较对照组减低。结论 彩色多普勒超声是DM患者下肢血管病变检查的有效手段，对早期诊断、预防及治疗具有重要的临床应用价值。? 　　【关键词】糖尿病；糖尿病下肢血管病变；超声检查；彩色多普勒 　　 　　Clinical diagnosis application of color doppler ultrasound on lower limbs’ angiopathy with diabetic patients 　　 　　ZHOU Ying.Department of Ultrasonic Diagnosis,the 5th Affliated Hospital of Zhengzhou University,Henan 450052,China 　　? 　　【Abstract】 Objective To evaluation the diagnosis application value of color doppler ultrasound on lower limbs’ angiopathy(LEAD)with Diabetic Patients(DM).Methods Medical check up on lower limb angiopathy through color doppler in the 106 cases who have been already diagnosized with dialers in contrast to 100 healthy volunteers.Results It is found out that 100(93．5%)out of the 106 diabetes mellitus patients had a theresclarerosis with Various severity，The vessel inside’s diameter of diabetes group was narrower than the control group，and the blood stream’s quantity of diabetes group was more decrease than the control group.Conclusion Color doppler can not only provide information on site and severity of low extremity arterial diseases but also provide reliable evidence for the diagnosis on the diabetes mellitus patients in the early stage of arterial disease with c1inical symptoms.? 　　【Key words】Diabetes; Lower limbs’ angiopathy; Supersonic inspection; Color doppler ultrasound 　　? 　　下肢血管病变(LEAD)是糖尿病(DM)最常见的并发症，患者轻者肢体疼痛、麻木、感觉异常及间歇跛行，重者可出现下肢缺血性坏疽，面临截肢的危险，下肢动脉栓塞是患者致残的主要原因[1]。下肢非糖尿病性动脉硬化和糖尿病性动脉硬化具有不同的发病过程和特点，而其临床表现有何异同，对临床处理的意义如何，是临床医生最关心的问题[2]。本文采用彩色多普勒超声诊断仪对DM患者进行下肢血管检测，探讨DM患者LEAD的诊断率、分布特点和形态学特征，旨在为临床提供早期诊断、预防和治疗依据。? 　　1 临床资料? 　　1．1 一般资料 选择2006年2月到2008年4月在本院超声诊断科门诊观察糖尿病患者106例(治疗组)。纳入标准：根据WHO诊断标准确诊为糖尿病，年龄34~80岁，患者对实验知情同意。排除标准：无下肢血管病变的患者。其中男56例，女50例，年龄36~80岁，平均58．3岁；病程2~40年，平均12．5年。正常对照组为同期体检的健康志愿者100例，自身因素与糖尿病组有可比性，一级亲属均无糖尿病史，空腹血糖、餐后2 h血糖、糖基血红蛋白、果糖胺均在正常范围。男5