高压氧综合治疗高频下降型突发性聋疗效剖析.docVIP

高压氧综合治疗高频下降型突发性聋疗效剖析 　　[摘要] 目的 分析高压氧综合治疗和常规药物治疗对突发性聋高频下降型的疗效。 方法 选择96例突发性聋高频下降型患者，随机分为高压氧组（HBO组）和药物组（对照组），HBO组在药物治疗基础上加用高压氧治疗。比较各组间的治疗效果。 结果 HBO组总有效率为81.25%，对照组总有效率为58.33%，两组间差异有统计学意义（P0.05）。两组听阈降低绝对值差异有统计学意义。 结论 高压氧结合药物治疗疗效显著，高压氧治疗可较好地改善突发性聋高频下降型患者的听力水平。 　　[关键词] 突发性；听觉丧失；纯音；测听法；高频下降；高压氧 　　[中图分类号] R764.437 [文献标识码] B [文章编号] 1673-9701（2017）02-0064-03 　　Effect of hyperbaric oxygen treatment on high-frequency sudden deafness 　　ZHANG Yanyan1 TANG Xuxia2 SHEN Qiang1 XIONG Gaoyun1 　　1.Department of Otolaryngology， Zhejiang Provincial Tongde Hospital， Hangzhou 310012， China； 2.First Clinical Medicine College， Zhejiang Chinese Medical University， Hangzhou 310006， China 　　[Abstract] Objective To analyze the effects of hyperbaric oxygen treatment and conventional drug therapy on high-frequency sudden deafness. Methods 96 patients with high-frequency sudden deafness were randomly divided into hyperbaric oxygen group（HBO group） and drug group（control group）. Patients in the HBO group were additionally given HBO treatment on the basis of drug therapy. The treatment effects were compared between two groups. Results The overall response rate was 81.25% in the HBO group， and was 58.33% in the control group， showing significant difference（P0.05）. There was significant difference between the two groups in reducing the absolute value of hearing threshold. Conclusion Hyperbaric oxygen treatment combined with drug therapy has significant effect on high-frequency sudden deafness， and can improve the listening ability of patients with high-frequency sudden deafness. 　　[Key words] Sudden； Hearing loss； Pure tone； Audiometry； High frequency impairment； High pressure oxygen 　　突?l性聋是指72 h内突然发生的、原因不明的感音神经性听力损失，至少在相邻的两个频率听力下降≥20 dBHL[1]。突发性聋根据听力损失累及的频率分为低频下降型、高频下降型、平坦下降型和全聋型。高频下降型为：2000 Hz（含）以上频率听力下降，至少4000、8000 Hz处听力损失≥20 dBHL；根据听力损失累及的程度：依据500、1000、2000、4000 Hz四个频率听阈的平均值进行分级：Ⅳ级（极重度）：≥81 dBHL；Ⅲ级（重度）：61～80 dBHL；Ⅱ级（中度）：41～60 dBHL；Ⅰ级（轻度）：26～40 dBHL；0级（正常）：≤25 dBHL[2]。中国突发性聋多中心临床研究数据显示：高频