磁共振弥散张量成像在颈髓急性损伤中的临床应用研究影像医学与核医学专业论文.docx

宁夏医科大学硕士研究生学位论文第一部分 宁夏医科大学硕士研究生学位论文 第一部分 英文摘要 II II Characteristics of DTI MR imaging on the normal cervical spinal cord in imaging ABSTRACT Objective To analyze parameters characteristics of the normal cervical spinal cord quantitatively in healthy volunteers by diffusion tensor imaging (DTI). Methods 30 healthy volunteers (men 18 women 12 age between 24-69years average age 39.8) were evenly divided into three age groups (less than 40 years, 41 to 59 years, over 60 years) according to year, including first group 10 cases, men 6,women 4; second group 10 cases, men 7, women 3; last group 10 cases, men 5,women 5.30 healthy volunteers were Performed Conventional T2WI，T1WI and axial DTI by using GE EXCITE II 1.5T MR. with ADC and FA maps generated ,30 volunteers got through DTI examination. On axial views, the ROI were placed in different levels of the cervical spinal cord (C1, C2, C3, C4, C5, C6, C7) and ROI were placed in the anterior region, posterior region and bilateral lateral region spinal tracts on axial views at C2 level. ADC and FA values of ROI were measured respectively Results Values of ADC and FA were correlated with age. with age increasing , FA values are low gradually, ADC values are high slightly. But there were not statistically significant in values of ADC and FA among different age-groups. On axial views, FA values at the level of C1 were significantly lower than those of other levels and ADC values at the level of C1were significantly higher than those of other levels (P0.05); FA values and ADC values at the level of C2 are in contrast (P0.05). On axial views FA values in the anterior region were significantly lower than others, while ADC values were significantly higher than others (P0.05); Conversely, FA values in the posterior region were significantly higher than others, while ADC values were significantly lower than others (P0.05). III III Conclusion DTI can clearly show the cervical spinal cord and analyze imaging characteristics of