低分子肝素应用对关节置换术出血量临床影响-外科学(骨外)专业论文.docx

安徽医科大学硕士学位论文 安徽医科大学硕士学位论文 - - 7 - arthroplasty(THA). Methods 85 patients unwent unilateral primary arthroplasty were divided into experimental group and control group by stratified randomization. The experimental group(LMWH) has 39 case,including 16 male patients and 23 female patients who’s average age was 69.3 years.In the experimental group there were 23 patients unwent THR and 16 patients unwent TKR.The contol group has 46 case,including 19 male patients and 27 female patients who’s average age was 68.5 years.In the contol group (no LMWH),there were 29 patients under THR and 17 patients under TKR.All patients’coagulation were checked normal,no DVT was carried with them through low extremity venous ultrasound and color sonography checking and the patients did not have the use of other anti-clotting drugs.Blood routine examination was done preoperatively and 2-4h postoperatively,hematocrit(Hct) was recorded,all patients’sta- ture and weight were measured preoperatively,blood loss and incision drainage were recorded.Through hidden blood loss introducting,We calculated the total blood loss.So some comments on the security of application of LMWH were made by these. Results The amount of blood loss was 1694ml in THR of the experimental group,it was 1570ml in TKR; The amount of blood loss was 1336ml in THR of the control group,it was 1302ml in TKR. there were different between them. Conclusion LMWH using in TJR increase the patients’bleeding volume;So we ought to notice to add the bood volume when we used LMWH for preventing DVT in TJR. Key words low molecular weight heparin total joint replacement deep vein throm- bosis pulmonary embolism bleeding volume - - 3 - 中英文名词对照表 英文缩写 TJR 英文名称 total joint replacement 中文名称 人工关节置换术 TKR THR total knee arthroplasty total hip arthroplasty 全膝关节置换术 全髋关节置换术 DVT PE deep vein thrombosis pulmonary embolism 深静脉栓塞 肺栓塞 VTE venous thromboembolism 静脉血栓栓塞症 LMWH low molecular weight heparin 低分子肝素 UFH BMI unfractionated heparin body mass index 普