降钙素原在区分细菌培养阳性主要致病菌中的意义.docVIP

降钙素原在区分细菌培养阳性主要致病菌中 的意义 ［ ］H的探讨降钙素原区分细菌培养阳性患者主要致病菌的意 义。方法选取包头医学院第二附属医院2015年12月?2016年12 月住院患者252例，同时做细菌培养和PCT检测，分析革兰氏阳性菌、 革兰氏阴性菌、真菌与PCT的相关性。结果120培养阳性患者，丼 中革兰氏扪性菌32 (26. 7%)例、革兰氏阴性菌69 (57. 5%)例、真菌 19(15. 8%)例。革兰氏阴性菌PCT中位数水平(1. 31 ug/L,IQR：0. 231? 9. 255)高于革兰氏阳性菌(0. 444 u g/L, IQR： 0. 139?2. 08), P0. 05； 革兰氏阳性菌以金黄色葡萄球菌和肠球菌最常见；革兰氏阴性菌以大 肠埃希菌和肺炎克雷伯菌最常见。结论革兰氏阴性菌感染患者血清 PCT的浓度高于革兰氏阳性菌感染患者。在区分革兰氏阳性菌、革兰 氏阴性菌感染方面PCT定量检测是一个有价值的标志物。 和著作权归原 所有， ［关键词］降钙素原；中位数；四分位数间距；革兰氏阳性菌；革兰 氏阴性菌 ［ ］R446.1 ［ ］A ［ ］2095-0616 (2017) 07-115-04 Significance of procalcitonin in division of main pathogens of bacterial culture ZHANG Li pi ng ZHAO Dong Clinical Laboratory, the Second Affiliated Hospital of Baotou Medical College, Baotou 014030, China ［Abstract］ Objective To explore the significance of procalcitonin in division of main pathogens of bacterial culture. Methods 252 hospitalized patients in the Second Affiliated Hospital of Baotou Medical College from December 2015 to December 2016 were selected. At the same time, bacterial culture and PCT detection were carried on. Correlations between gram positive bacteria and gram negative bacteria, fungi and PCT were analyzed. Results Among the 120 positive patients, there were 32 cases of gram positive bacteria 26. 7%, 69 caes of gram negative bacteria 57. 5% and 19 cases of fungi 15. 8%. Median PCT level in gram negative bacteria was 1. 31 u g/L, IQR： 0. 231-9. 255，which was significantly higher than that in gram positive bacteria with 0. 444 u g/L, IQR： 0. 139~2.08, P0. 05. The most common gram positive bacteria were Staphylococcus aureus and Enterococcus. The most common gram negative bacteria were Escherichia coli and Klebsiella pneumoniae. Conclusion Serum PCT concentration in gram negative bacterial infection is higher than that in gram positive bacteria infection. In the division of gram positive bacteria and gram negative bacteria infection, quantitative detection of PCT is a valuable marker. [Keywords] Procalcitonin； Media； Four digit