dcemri影像学特点与乳腺癌后指标的相关性研究.docx

优秀毕业论文 精品参考文献资料 西南医科大学硕士学位论文ER 西南医科大学硕士学位论文 ER表达呈显著负相关(r=一0．278 p=0．003)；与PR表达呈负相关 (r=一0．241 19--0．010)；与Her-2呈显著正相关(r=0．388 PO．001)； 与Ki一67呈显著正相关“=o．553 PO．001)；(6)淋巴结转移情况：与 ER、PR、Her．2无明显相关性；与Ki一67呈显著正相关“=O．41 1 P o．001)；(7)WHO组织学分级与ER、PR无明显相关性，与Her-2 呈显著正相关(r--0．303 p=0．001)；与Ki．67呈显著正相关(r= 0．307 19=0．001)；(8)Logistic回归多因素分析以及卡方检验、秩和 检验分别证实了DCE．MRI参数和乳腺癌预后指标之间具有相关性， 具有影响的不同预后指标的磁共振参数间又具有一定差异性。结论： 本研究认为DCE．MRI参数和乳腺癌预后指标之间具有相关性，可以 通过影像学特征间接推测预后指标的表达，并进行乳腺癌预后评估， 指导临床治疗方案的选择。 关键词：动态增强磁共振、乳腺癌、预后指标 万方数据 西南医科大学硕士学位论文Correlation 西南医科大学硕士学位论文 Correlation of DCE·-MRI imaging characteristics and prognostic indicator of breast cancer Abstract：0bjective：Through dynamic contrast-enhanced MRI (dynamic contrast-enhanced magnetic resonance imaging，DCE—MRI) imaging parameters of the collection，comprising：a tumor morphology, edge cases，strengthen the manner and time—signal curve，Explore the traditional prognostic factors in breast cancer：the correlation between lymph node metastasis，tumor size，WHO(World Health Organization) histological grade and molecular prognostic indicators，Find the regular between breast cancer from the molecular level to the biological and pathological features and to the MRI imaging．We are Trying to assess the prognosis of breast cancer patients by radiographic parameters，and to some extent guide the choice of clinical treatment programs．Methods： Collected from January 20 1 3 to December 20 1 5 during a visit to Mianyang Central Hospital breast surgery in breast cancer patients，they were selected from 1 1 3 cases of patients meet the requirements of the patients，all of them were female，unilateral disease，a total of 1 1 3 lesions， aged 32 to 65 years，an average of 46．96 4-7．80 1 years．1 1 3 cases of patients underwent preoperative breast MRI flat sweep+enhanced dynamic scanning，according to MRI breast Reporting and Data System (BI—RADS)describes morphological manifestations of breast cancer， 万方数据 西南医科大学硕士学位论文such 西南医科大学硕士学位论文 such as：enha