近年来出现的几类新概念动物疫苗.PDFVIP

生 物 工 程 学 报 张腾腾 等/近年来出现的几类新概念动物疫苗 1963 Chinese Journal of Biotechnology /cjbcn Dec. 25, 2018, 34(12): 1963−1973 DOI: 10.13345/j.cjb.180078 ©2018 Chin J Biotech, All rights reserved ·综 述· 1,2 1 1 2 1 张腾腾 ，罗玉子 ，孙元 ，李太元 ，仇华吉 1 150069 2 133002 , , , . . , 2018, 34(12): 1963–1973. Zhang TT, Luo YZ, Sun Y, et al. New-concept animal vaccines emerging in recent years. Chin J Biotech, 2018, 34(12): 1963–1973. 摘 要: 动物疫病流行广泛、传播迅速，严重危害养殖业的发展。疫苗接种是预防和控制动物传染病最有效的策 略之一。目前，随着生物技术的发展和疫病防控的需要，安全、高效、广谱、用量少、具有标记特征的新型疫苗 成为研发重点。文中就近年来出现的黏膜疫苗、长效与速效疫苗、嵌合疫苗、纳米颗粒疫苗等新概念动物疫苗的 发展、应用及优缺点进行了评述，并提出了其发展方向，以期为动物疫苗的研发提供借鉴。 : 新概念疫苗，动物疫病，研究进展 New-concept animal vaccines emerging in recent years 1,2 1 1 2 1 Tengteng Zhang , Yuzi Luo , Yuan Sun , Taiyuan Li , and Hua-Ji Qiu 1 State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, Heilongjiang, China 2 Agricultural College of Yanbian University, Yanji 133002, Jilin, China Abstract: Animal infectious diseases pose a serious and continuing threat to the animal health and cause huge economic losses throughout the world. Vaccination is one of the most effective solutions to prevent and control animal infectious diseases. With the development of biotechnologies and the need for disease prevention