介入联合中药治疗Ⅱ期以上血栓闭塞性脉管炎临床研究-中西医结合临床专业论文.docxVIP

介入联合中药治疗Ⅱ期以上血栓闭塞性脉管炎临床研究 万方数据 万方数据 ABSTRACT Objective To observe if combined interventional approach with traditional Chinese medicine (TCM) can better treat thromboangiitis obliterans (TAO) of Stage II and above than other approaches. Methods 60 patients with thromboangiitis obliterans of stageⅡ and above were randomly divided into two groups: 30 patients in group A treated with combined interventional therapy and traditional Chinese medicine (TCM), 30 patients in group B treated with interventional approach. Then, the therapeutic efficacies of the two groups were analyzed, including the cure rate, after one month、three months、six months、nine months and one year the recurrence rate, ankle brachial indexes (ABI), incidence of complications, the levels of C-reactive protein and erythrocyte sedimentation rate (ESR). Results compared with Group B, the cure rate in Group A markedly increased (P0.05). After one month, three months, six months, nine months and one year follow-ups, the recurrence rate of Group A is much lower than that the other Group (P0.05). And this difference is much more significant in a half year to one year’s follow-up.The combined treatment of interventional approach with traditional Chinese medicine increased the postoperative patency rate and it decreased the recurrence rate. For ABI, compared with Group B, Group A had a better efficacy in improving the artery occlusion(P0.05). Compared with Group B, Group A presented a lower incidence of complications (P0.05). After the treatment, the levels of C-reactive protein and ESR of the two groups all were lower than before, especial Group A (P0.05). The results indicate that the combined interventional approach with traditional Chinese medicine (TCM) have a better curative effect and lower incidence of complications. Conclusions The combined interventional traditional approach and Chinese medicine presents a better therapeutic effect in treating thromboangiitis obliterans. KEY WORDS Thromboangiitis