大数据与sci论文写作.pptVIP

大数据与SCI论文写作 金华市中心医院ICU 章仲恒 大数据 指的是所涉及的数据量规模巨大到无法通过人工，在合理时间内达到截取、管理、处理、并整理成为人类所能解读的信息。 “大数据”时代已经降临，在商业、经济及其他领域中，决策将日益基于数据和分析而作出，而并非基于经验和直觉。 -------2012 《纽约时报》 Data-driven decision making Leo Anthony Celi, Roger G. Mark, David J. Stone, and Robert A. Montgomery “Big Data” in the Intensive Care Unit. Closing the Data Loop, American Journal of Respiratory and Critical Care Medicine, Vol. 187, No. 11 (2013), pp. 1157-1160. Elysium Big data-critical care Why use database? efficient use of research investments. Unethical Greater generalizability (large registries and administrative data) Primary data collection is too onerous (5- or 10-yr follow-ups) more precise estimate of effect (large sample) Examples Data Sources SELECTING A DATA SOURCE Data Quality Taxonomy of the Question Mapping the Question to the Data Data Quality Black N, Payne M: Directory of clinical databases: Improving and promoting their use. Qual Saf Health Care 2003; 12:348–352 Taxonomy of the Question My experience with MIMIC-2 public research archive of data collected from patients in intensive care units （30000 ） Open access, freely availiable (/mimic2/) High resolution Beth Israel Deaconess Medical Center (Boston) Technology provided by MIT. Latest version: 2001-2008 Access to MIMIC-2 Figure 1. Relationship between initial iCa (upper panel) and logit transformed mortality by using Lowess smoothing technique. Zhang Z, Xu X, Ni H, Deng H (2014) Predictive Value of Ionized Calcium in Critically Ill Patients: An Analysis of a Large Clinical Database MIMIC II. PLoS ONE 9(4): e95204. doi:10.1371/journal.pone.0095204 /article/info:doi/10.1371/journal.pone.0095204 Table 3. Multivariable logistic regression categorizing calcium values into intervals by using linear spline function. Zhang Z, Xu X, Ni H, Deng H (2014) Predictive Value of Ionized Calcium in Critically Ill Patients: An Analysis of a Large Clinical Database MIMIC II. PLoS ONE 9(4): e95204. doi:10.1371/journal.pone.0095