降糖舒络方治疗2型糖尿病周围神经病变的中医理论探讨与临床研究-中医内科专业论文.docxVIP

中文摘要关键词：气阴两虚夹瘀夹风证，糖尿病周围神经病变，肌电图，降糖舒 中文摘要 关键词：气阴两虚夹瘀夹风证，糖尿病周围神经病变，肌电图，降糖舒 络方 目的：观察以益气养阴活血疏风之法组成之降糖舒络方治疗2型糖尿病 周围神经病变的临床疗效，通过临床观察的疗效，尝试寻找病iir-N辨的新途 径，开发2型糖尿病周围神经病变的临床有效疗法。 方法：对台湾景新中医诊所收治的2型糖尿病患者进行分析，选择2004 年10月至2006年1月门诊治疗的56例2型糖尿病周围神经病变的气阴两虚 夹瘀夹风证患者分为两组，在给予迭美康的基本降糖治疗基础上分别一组给 予弥可保，另一组给予中药降糖舒络方，观察治疗前后2型糖尿病周围神经 病变及中医证候疗效，并观察血糖、糖化血红蛋白、Tc、TG及肌电图之变化 及疗效。 结果：降糖舒络方治疗2型糖尿病周围神经病变(气阴两虚夹瘀夹风证) 总有效率为89．29％(弥可保为60．72％)，中医证候改善率为92．9％(弥可保为 67．9％)，与达美康有协同降糖作用，并可降低糖化血红蛋白，降低Tc、TG值， 增进血流，并提升神经传导速率。 结论2型糖尿病周围神经病变其基本病机为气阴两虚夹瘀夹风，益气养 阴活血疏风法是其有效治法，降糖舒络方可协助降糖，降低Tc、TG值，促进 血瀛并增进其神经传导速度，是治疗2型糖尿病周围神经病变的有效组方。 TCM TCM academic discuss and therapeutic effect observation of Jiangtangshuluo Formula on diabetic peripheral neuropathy (English Abstract) Objecfive To investigate the therapeutic effect of of Jiangtangshuluo Formula(JTSLF)on diabetic peripheral neuropathy(DPN)in the pattern of deficiency of Qi and Ym larded with stasis and Feng(DQYSF)，and to search for new ways and means oftreating to both disease and traditional Chinese medicine(TCM)pattern． Methods Fifty-six cases谢t11 DPN in the pattem ofDQYSF hospitalized in Taiwan Jinxin Clinique of TCM were randomly divided into treating group(TO) and controlling one(CO)，based on fundamental therapy of Diamicron(Gliclazide) in each．At the saffle time，the cases in TG were treated by JTSLF while those in CG were treated by Methycobal．Then，all the cases in both groups were observed on and compared with their index changes in symptoms，signs，blood sugar, glycohemoglobin，total cholesterol，triglyceride and electromyography． Results The total effective rate was 89．29％In TG compared 60．72％with tllat of CGIjand the improving rate in TCM symptoms was 92．9％．The therapeutic effect of JTSLF on such indexes like glycohemoglobin，total cholesterol and triglyceride was significantly superior to that of CCLI The effect ofblood sugar-reducing cooperated with Diamicron and of blood stream—improving were also significantly marked in TG than that in CG Furthermore，the index o