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- 2019-04-05 发布于上海
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Abstract
Objective
By taking swimming endurance trained rats to the Meridian Theory Prescription drug selection compound preparation, rats in each group were compared under different functional states associated biochemical markers of myocardial tissue differences, explore the mechanism of exercise-induced myocardial injury and sports training, in the final The theoretical alternative drugs compound in protecting myocardial tissue injury induced by oxidative stress, normalized by the theoretical practice serving the movement to provide more scientific basis.
Methods
Select 120 male wistar rats were randomly divided into four major groups, namely the control group (A group), medication group (B), exercise group (C) and taking exercise group (D), n = 30. The adaptive feeding rats a week after the animal room, exercise group exercise group and medication for 6 weeks swimming training and before training TCM decoction orally 1h after 6 weeks and then every big rats were randomly divided into a quiet state, Exhausted Exhausted immediately after recovery after 12h and three subgroups, and in the appropriate moment decapitated quickly take heart, into the -84 ℃ ultra-low temperature freezer, measured CK (creatine kinase), Na +-K +-ATPase (Na +-K +-ATPase enzyme), MDA (malondialdehyde), SOD (superoxide dismutase). All data SPSS19.0 software for statistical analysis.
Results
quiet state, compared with the control, myocardial MDA content in the exercise group, medication group, taking exercise group was significantly lower (P 0.05); SOD activity, Na +-K
+-ATPase activity in the exercise group, medication group, medication exercise group was significantly higher (P 0.05), the other groups had no significant difference between; CK activity in each group had no significant difference (P 0.05).
exhaustive instant status, compared with the control group, myocardial MDA content in the exercise group, medication group, taking exercise were significantly lower (P 0.05
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