补肾固齿丸对中老年慢性牙周炎的临床效果及安全性观察.docxVIP

补肾固齿丸对中老年慢性牙周炎的临床效果及安全性观察 承德医学院附属医院口腔科河北承德067000 第一作者：孟凡利，主治医师，木科。第二作者：霍峰，主任医师，硕士。第三 作者：李乐，副主任医师，硕士。 通讯作者：张艳波， 主治医师，木科。 ［摘要］目的观察补肾固齿丸对中老年慢性牙周炎的临床效果及安全性。方法 选择木院2015年1月至2015年10月的中老年慢性牙周炎患者54例，分为实验 组和对照组，两组均给予牙周基础治疗，实验组在牙周基础治疗后，给予补肾固 齿丸治疗，对照组不服药。3个月后复查，观察各项牙周指数的变化、治疗效果 及不良反应。结果比较两组治疗前后全口牙龈指数(GL)、菌斑指数(PLI)、牙 周探诊深度(PPD)、附着水平(PAL),结果显示治疗前两组比较无显著性差异(P 0.05),治疗后两组上述指标均明显下降(PV0.05),实验组下降程度大于对照组， 且组间差异有统计学意义(P0.05);有效率实验组明显高于对照组，且组间差 异有统计学意义(P0.05)；观察实验组使用补肾固齿丸患者均无明显不良反应 发生。结论补肾固齿丸联合牙周基础治疗对中老年慢性牙周炎疗效显著，无明 显不良反应发生、使用安全，值得在临床上推广应用。 ［关键词］补肾固齿丸；中老年慢性牙周炎；牙周基础治疗；安全性 【中图分类号】R548.2【文献标识码】A【文章编号】1001-5213(2016)09-0096-02 Effect and safety of Bushenguchi pill on middle-aged and elderly patients with chronic periodontitis ［AbstractJObjective To observe the effect and safety of Bushenguchi pill on middle-aged and elderly patie nts with chr onic period on titis. Methods 54 middle-aged and elderly patients with chronic periodontitis were selected and randomly divided into study group and control group. All patients in two groups received period on tai initial therapy, and patie nts in study group received Bushe nguchi pill. 3 mon ths later, the cha nges of period on tai in dex, treatme nt effect and adverse reaction were observed? Before treatment, there was no sign讦icant differenee between the two groups in the whole mouth (GL), plaque index (PLI), periodontal probing depth (PPD) and attachment level (PAL) (p0.05), which of two groups were significantly decreased (p0.05), and those of study group were lower than those of the control group, and differenee between the two groups has statistical sign ifica nee (p0.05) ;The effective rate of the study group was sign讦icantly higher than that of the control group, and there was sign讦icant difference between the two groups (p0.05);There was no obvious adverse reaction in the study group ? Con clusi on Bushe nguchi pill combi ned with period on tai in itial therapy on middle-aged and elderly patients with chronic periodontitis can achieve sign讦i