活血化坚汤治疗聚合性痤疮（血瘀痰凝证）临床疗效观察-中医外科学(皮肤)专业论文.docxVIP

成都 成都中医药大学硕士学位论文 万方数据 万方数据 中文摘要 目的：探讨和评估活血化坚汤治疗聚合性痤疮的作用机理和临床疗效，分析其优 势,从而给临床治疗聚合性痤疮提供一种安全有效的治疗方法。 方法：选择 100 例符合纳入标准的聚合性痤疮患者，随机分为两组。治疗组 50 例,内服活血化坚汤；对照组 50 例，予异维 A 酸软胶囊口服，两组均外擦克林霉 素磷酸酯凝胶。每周复诊,4 周为一个疗程，连续观察 8 周,疗程结束后对观察记 录的积分进行统计学分析,判定疗效。 结果：治疗 8 周后，治疗组和对照组有效率分别是 70.83%、62.5%，差异无统计 学意义（P＞0.05），说明两组总疗效相当。对两组复发率和不良反应发生率的比 较，差异有统计学意义（P＜0.05），说明治疗组在减少复发，降低不良反应方面 优于对照组。 结论：活血化坚汤对聚合性痤疮有良好的治疗作用，且复发率少，治疗过程中不 良反应发生率低，患者易于接受，具有临床推广价值。 关键词：活血化坚汤 异维 A 酸软胶囊 聚合性痤疮 血瘀痰凝证 1 Abstract Objective:To explore the diagnosis and treatment and evaluation of invigorate the Huoxue Huajian soup polymerized acne,the mechanism and clinical curative effect,analyses their advantages and thus to the clinical treatment of polymerized acne to provide a safe and effective treatment. Methods ： Select 100 cases included in the standard of polymerized acne patients,randomly divided into two groups.Treatment group(50 cases) take orally Huoxue Huajian soup.The control group(50 cases) take orally D A weakness in the capsule,both groups of topical clindamycin phosphate gel.Weekly visit,4 weeks for a period of treatment,observation of eight weeks in a row,after the treatment of observation records for the atatistical analysis of the integral judge curative effect. Results：8 weeks after treatment,the treatment group and control group effectiveness respectively is 70.83% and 62.5%,there was no statistically significant difference(P＞ 0.05),two groups of total curative effect quite.On the comparison of two groups of recurrence rate and the incidence of adverse reactions,the difference was statistically significant(P ＜ 0.05),the treatment group in reducing relapse,reduce the adverse reaction is better than that in control group. Conclusion：Huoxue Huajian soup which is easy to be accepted by the patient,has the curative effect to treat the polymerized acne,and low recurrence rate,low incidence of adverse reactions in the process of treatment,has clinical value. Key words ： Huoxue Huajian soup D A weakness in the c