络脉舒通颗粒剂治疗不稳定型心绞痛的临床观察-中医内科学专业毕业论文.docxVIP

x眦18、提要 x眦18、 提要 目的：观察络脉舒通颗粒剂治疗不稳定型心绞痛的临床疗效。方法：60例不稳 定型心绞痛患者随机分为络脉舒通颗粒剂组(治疗组)31例，通心络胶囊组(对照 组)29例。两组均用常规西药治疗，同时，治疗组予络脉舒通颗粒剂，对照组予通 心络胶囊。观察治疗前后临床症状和实验室指标的变化。结果：治疗组心绞痛缓解总 有效率为93．55％，显效率为70．97％；心电图疗效总有效率为93．55％，显效率为35．48％； 症状改善总有效率96．77％，显效率61．29％，与对照组比较有显著性差异(PO．05)。 显著降低Tc、T6、n bH、n bL、n P、Fbg，与对照组比较有显著性差异(PO．05或 PO．01)。明显降低TXB。、ET—l、APTT、TT，升高N0，与治疗前相比具有显著性差异 (PO．05或PO．01)。结论：痰瘀是本病的关键病机，清热化痰、祛瘀通络是治疗不 稳定型心绞痛的一种有效治疗方法。 关键词络脉舒通颗粒剂；不稳定型心绞痛；临床观察 Cl Cl inieaI Observation on Treating Unstable Angi rla by Luoma i shutong Grarlu I e SpeciaI ity：InternaI Medioine of TraditionaI Chinese Medicine Author：Zhao Hao Tutor：Bao Pei rong Abstract Obiective：To observe the clillical effect of Luomaishutong Granule on unstable angina。Methods：Sixty patients of coronary heart disease(CHD) wi th unstable angina were divided randomly into treatment group(31 cases) and control group(29 cases)．Conventional western medical therapy was given to both groups．At the same time．the treatment group received Luomaishutong Granule and the control group received Tongxinluo Capsule．The changes of cl im cal symptoms and laboratory indexes in a11 the patients were observed before and after treatment． Resu I ts：In the treatment group，the total effectire rate of relieving angina，improving ECG and meliorating symptoms were respectively 93。55％，93。55％and 96。77％：the corresponding remarkable rate were respectively 70．97％，35．48％，辍。29％，which were signi ficantIy better than those of the control group。PO．05．The level of TC、TG、rlbH、nbL、qP and }、bg were decreased remarkabIy in the treatment group．which were statistical 1Y di fi‘erent compared with those of the control group．PO．05 or PO．01．Meanwhi le the level or TXB2、ET、APTT、TT were decreased and the level of NO WaS increased remarkablY after treatment，which were statistically different compared with those before treatment。 ConelusiOrl：The phlegm and the stasis are the cri t ical pathogenesis of unstable angina．The method of elearlng heat transf’orming